Central delivery of Dicer-substrate siRNA: a direct application for pain research (Q46559934)

23 December 2017

title

Central delivery of Dicer-substrate siRNA: a direct application for pain research (English)

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23 December 2017

author

Mark A. Behlke

8

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23 December 2017

author name string

Louis Doré-Savard

1

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23 December 2017

Geneviève Roussy

2

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23 December 2017

Marc-André Dansereau

3

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23 December 2017

Michael A Collingwood

4

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23 December 2017

Kim A Lennox

5

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23 December 2017

Scott D Rose

6

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23 December 2017

Nicolas Beaudet

7

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23 December 2017

Philippe Sarret

9

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23 December 2017

publication date

3 June 2008

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23 December 2017

published in

Molecular Therapy

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23 December 2017

volume

16

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23 December 2017

issue

7

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23 December 2017

page(s)

1331-1339

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23 December 2017

https://api.crossref.org/works/10.1038%2FMT.2008.98

1 reference

7 January 2021

RNA interference: biology, mechanism, and applications

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

First clinical data on RNAi

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Progress towards in vivo use of siRNAs

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Therapeutic potential of RNA interference for neurological disorders

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Synthetic shRNAs as potent RNAi triggers.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Functional polarity is introduced by Dicer processing of short substrate RNAs

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Rational design and in vitro and in vivo delivery of Dicer substrate siRNA.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Inhibition of hepatitis C virus gene expression by small interfering RNAs using a tri-cistronic full-length viral replicon and a transient mouse model

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Drug and gene delivery to the brain: the vascular route

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

siRNA relieves chronic neuropathic pain

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Differential role of N-type calcium channel splice isoforms in pain.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

A single siRNA suppresses fatal encephalitis induced by two different flaviviruses

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Small interfering RNA-mediated selective knockdown of Na(V)1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Potent spinal analgesia elicited through stimulation of NTS2 neurotensin receptors

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Neurotensin and pain modulation

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Comparison of mice deficient in the high- or low-affinity neurotensin receptors, Ntsr1 or Ntsr2, reveals a novel function for Ntsr2 in thermal nociception

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

The partial agonist properties of levocabastine in neurotensin-induced analgesia

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

RNAi therapeutics: principles, prospects and challenges

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Chronic intrathecal cannulation enhances nociceptive responses in rats

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Intrathecal catheterization alone induces neuroimmune activation in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Visual impairment following epidural fluid injections and epiduroscopy: a review

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Spinal delivery of analgesics in experimental models of pain and analgesia

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Activation of the mammalian immune system by siRNAs.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

2'-O-methyl-modified RNAs act as TLR7 antagonists

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Minimizing the risk of reporting false positives in large-scale RNAi screens

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

The induction of inflammation by adenovirus vectors used for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Delivery of siRNA from lyophilized polymeric surfaces

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Modified 27-nt dsRNAs with dramatically enhanced stability in serum and long-term RNAi activity

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

MicroRNA-directed cleavage of HOXB8 mRNA

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

RNAi pathway is functional in peripheral nerve axons.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Use of opioid medications for chronic noncancer pain syndromes in primary care

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

An evidence-based update on nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Responsible prescribing of opioids for the management of chronic pain

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Management of chronic noncancer pain in the primary care setting

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.98

7 January 2021

Identifiers

DOI

10.1038/MT.2008.98

1 reference

23 December 2017

PubMed ID

18523447

1 reference

23 December 2017