Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury (Q46503010)

22 December 2017

title

Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury (English)

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22 December 2017

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6

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22 December 2017

author name string

Christopher K Means

1

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22 December 2017

Chun-Yang Xiao

2

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22 December 2017

Zhuangjie Li

3

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22 December 2017

Tong Zhang

4

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22 December 2017

Jeffrey H Omens

5

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22 December 2017

Jerold Chun

7

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22 December 2017

Joan Heller Brown

8

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22 December 2017

publication date

9 February 2007

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22 December 2017

American Journal of Physiology Heart and Circulatory Physiology

published in

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22 December 2017

volume

292

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22 December 2017

issue

6

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22 December 2017

page(s)

H2944-51

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22 December 2017

Cardiomyocyte apoptosis induced by Galphaq signaling is mediated by permeability transition pore formation and activation of the mitochondrial death pathway.

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Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion

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Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

21 January 2018

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Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

21 January 2018

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Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3

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Sphingosine kinase activation mediates ischemic preconditioning in murine heart

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Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts

21 January 2018

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Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling

21 January 2018

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The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes

21 January 2018

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Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction

21 January 2018

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Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection

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21 January 2018

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21 January 2018

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Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

21 January 2018

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Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size following ischemia-reperfusion injury in vivo

21 January 2018

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Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells

21 January 2018

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HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3.

21 January 2018

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The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

21 January 2018

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21 January 2018

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Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes.

21 January 2018

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21 January 2018

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21 January 2018

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Ischemic preconditioning activates phosphatidylinositol-3-kinase upstream of protein kinase C

21 January 2018

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Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: a study using mice lacking their respective receptors

21 January 2018

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The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity

21 January 2018

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10.1152/AJPHEART.01331.2006

21 January 2018

Identifiers

DOI

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22 December 2017

PubMed ID

17293497

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22 December 2017