Translocation-arrested apolipoprotein B evades proteasome degradation via a sterol-sensitive block in ubiquitin conjugation (Q46415806)

22 December 2017

title

Translocation-arrested apolipoprotein B evades proteasome degradation via a sterol-sensitive block in ubiquitin conjugation (English)

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22 December 2017

ubiquitin-proteasome system

main subject

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author name string

E Z Du

1

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22 December 2017

J F Fleming

2

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22 December 2017

S L Wang

3

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22 December 2017

G M Spitsen

4

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22 December 2017

R A Davis

5

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22 December 2017

language of work or name

English

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publication date

1 January 1999

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22 December 2017

Journal of Biological Chemistry

published in

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22 December 2017

volume

274

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22 December 2017

issue

3

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22 December 2017

page(s)

1856-1862

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22 December 2017

Biosynthesis of apolipoprotein B48-containing lipoproteins. Regulation by novel post-transcriptional mechanisms

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Bile acid metabolism in hereditary forms of hypertriglyceridemia: evidence for an increased synthesis rate in monogenic familial hypertriglyceridemia

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Microsomal triglyceride transfer protein

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In HepG2 cells, translocation, not degradation, determines the fate of the de novo synthesized apolipoprotein B.

21 January 2018

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Studies on intracellular translocation of apolipoprotein B in a permeabilized HepG2 system

21 January 2018

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Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia

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Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia

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Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein

21 January 2018

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Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes.

21 January 2018

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Coordinate regulation of lipogenesis, the assembly and secretion of apolipoprotein B-containing lipoproteins by sterol response element binding protein 1.

21 January 2018

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Translocation of apolipoprotein B across the endoplasmic reticulum is blocked in a nonhepatic cell line

21 January 2018

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Hygromycin B Phosphotransferase as a Selectable Marker for DNA Transfer Experiments with Higher Eucaryotic Cells

21 January 2018

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Degradation of CFTR by the ubiquitin-proteasome pathway

21 January 2018

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Structural relationship of human apolipoprotein B48 to apolipoprotein B100.

21 January 2018

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Russell bodies: a general response of secretory cells to synthesis of a mutant immunoglobulin which can neither exit from, nor be degraded in, the endoplasmic reticulum

21 January 2018

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Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

21 January 2018

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Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

21 January 2018

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How proteolysis drives the cell cycle

21 January 2018

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Covalent modification of PML by the sentrin family of ubiquitin-like proteins

21 January 2018

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Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p

21 January 2018

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Complete protein sequence and identification of structural domains of human apolipoprotein B

21 January 2018

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A transmembrane form of the prion protein in neurodegenerative disease

21 January 2018

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Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

21 January 2018

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Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

21 January 2018

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Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis.

21 January 2018

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Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

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Cholesterol 7 alpha-hydroxylase is up-regulated by the competitive inhibitor 7-oxocholesterol in rat liver.

21 January 2018

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Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100

21 January 2018

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Stable isotopes show a direct relation between VLDL apoB overproduction and serum triglyceride levels and indicate a metabolically and biochemically coherent basis for familial combined hyperlipidemia

21 January 2018

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Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia

21 January 2018

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Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step

21 January 2018

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The microsomal triglyceride transfer protein catalyzes the post-translational assembly of apolipoprotein B-100 very low density lipoprotein in McA-RH7777 cells

21 January 2018

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Ubiquitin-proteasome pathway mediates intracellular degradation of apolipoprotein B

21 January 2018

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The degradation of apolipoprotein B100 is mediated by the ubiquitin-proteasome pathway and involves heat shock protein 70

21 January 2018

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Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.3.1856

Mapping of human apolipoprotein B antigenic determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.3.1856

Relationship between diurnal variations in biosynthesis cholesterol and bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.3.1856

Effects of interruption of the enterohepatic circulation of bile acids on the transport of very low density-lipoprotein triglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.3.1856

21 January 2018

Identifiers

DOI

10.1074/JBC.274.3.1856

1 reference

22 December 2017

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22 December 2017