Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation (Q46402539)

21 December 2017

title

Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation (English)

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21 December 2017

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6

Leif Hertz

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21 December 2017

Baoman Li

1

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21 December 2017

Shiquen Zhang

2

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21 December 2017

Hongyan Zhang

3

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21 December 2017

Weiwei Nu

4

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21 December 2017

Liping Cai

5

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21 December 2017

Liang Peng

7

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21 December 2017

publication date

29 August 2008

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21 December 2017

published in

Psychopharmacology

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21 December 2017

volume

201

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21 December 2017

issue

3

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21 December 2017

page(s)

443-458

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21 December 2017

https://scigraph.springernature.com/pub.10.1007/s00213-008-1306-5

exact match

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cites work

The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2B) receptor gene products: comparison with 5-HT2A and 5-HT2C receptors

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The c-fos proto-oncogene is a target for transactivation by the p53 tumor suppressor.

21 January 2018

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Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

21 January 2018

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A comparison of brain and serum pharmacokinetics of R-fluoxetine and racemic fluoxetine: A 19-F MRS study

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New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

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5-hydroxytryptamine 2B receptor regulates cell-cycle progression: cross-talk with tyrosine kinase pathways

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Activation of 5-HT2B receptors in the medial amygdala causes anxiolysis in the social interaction test in the rat.

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Molecular biology of serotonin receptors

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Detection of 5-hydroxytryptamine2 receptors by radioligand binding, northern blot analysis, and Ca2+ responses in rat primary astrocyte cultures.

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Expression of serotonin receptors in human fetal astrocytes and glioma cell lines: a possible role in glioma cell proliferation and migration.

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Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study.

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Cultured astrocytes express messenger RNA for multiple serotonin receptor subtypes, without functional coupling of 5-HT1 receptor subtypes to adenylyl cyclase.

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Opposing regulation of cell proliferation by retinoic acid and the serotonin2B receptor in the mouse frontonasal mass

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R-fluoxetine increases extracellular DA, NE, as well as 5-HT in rat prefrontal cortex and hypothalamus: an in vivo microdialysis and receptor binding study

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5-Hydroxytryptamine2B receptors stimulate Ca2+ increases in cultured astrocytes from three different brain regions

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Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding

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The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification

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Reversal of learned helplessness by selective serotonin reuptake inhibitors in rats is not dependent on 5-HT availability.

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Tyrosine kinase inhibition: an approach to drug development

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Brain pharmacokinetics and tissue distribution in vivo of fluvoxamine and fluoxetine by fluorine magnetic resonance spectroscopy

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Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells

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Up-regulation of 5-HT2B receptor density and receptor-mediated glycogenolysis in mouse astrocytes by long-term fluoxetine administration

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12 December 2020

Stimulation of glycogenolysis in astrocytes by fluoxetine, an antidepressant acting like 5-HT.

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12 December 2020

Transcriptional induction of FosB/DeltaFosB gene by mechanical stress in osteoblasts.

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12 December 2020

Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts

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12 December 2020

Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor

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12 December 2020

Further evidence that fluoxetine interacts with a 5-HT2C receptor in glial cells

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12 December 2020

Serotonin and neuronal growth factors - a convergence of signaling pathways

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12 December 2020

Functional studies in cultured astrocytes

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The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

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MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes

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Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog

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Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors.

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Brain kinetics of paroxetine and fluoxetine on the third day of placebo substitution: a fluorine MRS study

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Molecular cloning, functional expression, and mRNA tissue distribution of the human 5-hydroxytryptamine2B receptor

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Signalling pathways for transactivation by dexmedetomidine of epidermal growth factor receptors in astrocytes and its paracrine effect on neurons

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Antidepressants increase glial cell line-derived neurotrophic factor production through monoamine-independent activation of protein tyrosine kinase and extracellular signal-regulated kinase in glial cells

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Blockage of 5HT2C serotonin receptors by fluoxetine (Prozac)

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12 December 2020

Involvement of epidermal growth factor receptor in chemically induced mouse bladder tumour progression

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12 December 2020

5-Hydroxytryptamine2-family receptors (5-hydroxytryptamine2A, 5-hydroxytryptamine2B, 5-hydroxytryptamine2C): where structure meets function

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12 December 2020

Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress.

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12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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12 December 2020

Pharmacological characterisation of human 5-HT2 receptor subtypes

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12 December 2020

Immunohistochemical localisation of the serotonin 5-HT2B receptor in mouse gut, cardiovascular system, and brain

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12 December 2020

5-HT2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine

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Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-kappaB in cardiomyocytes

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12 December 2020

Drugs and valvular heart disease

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12 December 2020

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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12 December 2020

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

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12 December 2020

5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells

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12 December 2020

Dependence of hepatocytic autophagy on intracellularly sequestered calcium

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12 December 2020

Fluoxetine treatment of depression. Clinical effects, drug concentrations and monoamine metabolites and N-terminally extended substance P in cerebrospinal fluid.

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12 December 2020

A novel role for serotonin in heart

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12 December 2020

10.1007/S00213-008-1306-5

Identifiers

DOI

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21 December 2017

PubMed ID

18758753

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21 December 2017