A scalable platform to identify fungal secondary metabolites and their gene clusters (Q46352630)

http://europepmc.org/abstract/PMC/5577364

21 December 2017

title

A scalable platform to identify fungal secondary metabolites and their gene clusters (English)

1 reference

http://europepmc.org/abstract/PMC/5577364

21 December 2017

1 reference

1 reference

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14

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31 May 2020

Maria H Verdan

5

1 reference

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31 May 2020

Paul M. Thomas

12

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31 May 2020

Neil Kelleher

17

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604695%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Kenneth D Clevenger

1

1 reference

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31 May 2020

Jin Woo Bok

2

1 reference

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31 May 2020

Rosa Ye

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604695%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Galen P Miley

4

1 reference

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31 May 2020

Thomas Velk

6

1 reference

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31 May 2020

Cynthia Chen

7

1 reference

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31 May 2020

KaHoua Yang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604695%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Matthew T Robey

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604695%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Peng Gao

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604695%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Matthew Lamprecht

11

1 reference

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31 May 2020

Md Nurul Islam

13

1 reference

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31 May 2020

Chengcang C Wu

15

1 reference

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31 May 2020

Nancy P Keller

16

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31 May 2020

publication date

12 June 2017

1 reference

http://europepmc.org/abstract/PMC/5577364

21 December 2017

full work available at URL

https://europepmc.org/articles/pmc5577364?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/nchembio.2408?email=unpaywall_01@example.com

published in

Nature Chemical Biology

1 reference

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31 May 2020

volume

13

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31 May 2020

issue

8

1 reference

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31 May 2020

page(s)

895-901

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604695%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/nchembio.2408?email=unpaywall_01@example.com

access restriction status

open access

1 reference

inferred from online access status

exact match

https://scigraph.springernature.com/pub.10.1038/nchembio.2408

0 references

cites work

Sequencing and functional annotation of the whole genome of the filamentous fungus Aspergillus westerdijkiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Modern mass spectrometry for synthetic biology and structure-based discovery of natural products.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Understanding Programming of Fungal Iterative Polyketide Synthases: The Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Minimum Information about a Biosynthetic Gene cluster.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Fungal artificial chromosomes for mining of the fungal secondary metabolome

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Large-scale metabolomics reveals a complex response of Aspergillus nidulans to epigenetic perturbation

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Heterologous production of fungal secondary metabolites in Aspergilli

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Methylation-dependent acyl transfer between polyketide synthase and nonribosomal peptide synthetase modules in fungal natural product biosynthesis

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Phylogeny, identification and nomenclature of the genus Aspergillus

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Reconstructing fungal natural product biosynthetic pathways

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Mass spectrometry of natural products: current, emerging and future technologies

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Molecular and chemical characterization of the biosynthesis of the 6-MSA-derived meroterpenoid yanuthone D in Aspergillus niger.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Heterologous reconstitution of the intact geodin gene cluster in Aspergillus nidulans through a simple and versatile PCR based approach

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

An efficient system for heterologous expression of secondary metabolite genes in Aspergillus nidulans

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Accurate prediction of secondary metabolite gene clusters in filamentous fungi

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

The Fungi: 1, 2, 3 ... 5.1 million species?

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

SMURF: Genomic mapping of fungal secondary metabolite clusters

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Anthranilate-activating modules from fungal nonribosomal peptide assembly lines

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

ProteoWizard: open source software for rapid proteomics tools development

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Molecular genetic mining of the Aspergillus secondary metabolome: discovery of the emericellamide biosynthetic pathway

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

LaeA, a regulator of secondary metabolism in Aspergillus spp

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Recombineering: a powerful new tool for mouse functional genomics

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Techniques: Recombinogenic engineering--new options for cloning and manipulating DNA.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Insights into natural products biosynthesis from analysis of 490 polyketide synthases from Fusarium

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Automatic chemical structure annotation of an LC-MS(n) based metabolic profile from green tea.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

First heterologous reconstruction of a complete functional fungal biosynthetic multigene cluster.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Inhibition of the human chemokine receptor CCR5 by variecolin and variecolol and isolation of four new variecolin analogues, emericolins A-D, from Emericella aurantiobrunnea

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5577364

Characterisation of 3-methylorcinaldehyde synthase (MOS) in Acremonium strictum: first observation of a reductive release mechanism during polyketide biosynthesis

15 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2408

7 January 2021

Engineering of Aspergillus niger for the production of secondary metabolites.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2408

7 January 2021

Benzomalvin E, an indoleamine 2,3-dioxygenase inhibitor isolated from Penicillium sp. FN070315

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2408

7 January 2021

Benzomalvins, new substance P inhibitors from a Penicillium sp

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2408

7 January 2021

Cytotoxic sesterterpenes, 6-epi-ophiobolin G and 6-epi-ophiobolin N, from marine derived fungus Emericella variecolor GF10

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2408

7 January 2021

Ophiobolin Sesterterpenoids and Pyrrolidine Alkaloids from the Sponge-Derived Fungus Aspergillus ustus

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2408

7 January 2021

Toward the total synthesis of variecolin

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2408

7 January 2021

Cloning and heterologous expression of the penicillin biosynthetic gene cluster from penicillum chrysogenum

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28604695

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCHEMBIO.2408

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604695%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604695%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

28604695

1 reference