A new generation of peptide-based inhibitors targeting HIV-1 reverse transcriptase conformational flexibility (Q46295068)

21 December 2017

title

A new generation of peptide-based inhibitors targeting HIV-1 reverse transcriptase conformational flexibility (English)

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21 December 2017

Nathalie Dereuddre-Bosquet

author

4

object named as

Nathalie Bosquet

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21 December 2017

author name string

Audrey Agopian

1

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21 December 2017

Edwige Gros

2

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21 December 2017

Gudrun Aldrian-Herrada

3

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21 December 2017

Pascal Clayette

5

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21 December 2017

Gilles Divita

6

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21 December 2017

language of work or name

English

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publication date

23 October 2008

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21 December 2017

Journal of Biological Chemistry

published in

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21 December 2017

volume

284

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21 December 2017

issue

1

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21 December 2017

page(s)

254-264

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21 December 2017

HIV/AIDS epidemiology, pathogenesis, prevention, and treatment

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

The design of drugs for HIV and HCV

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Alterations to the primer grip of p66 HIV-1 reverse transcriptase and their consequences for template-primer utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Contribution of the p51 subunit of HIV-1 reverse transcriptase to enzyme processivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Interface peptides as structure-based human immunodeficiency virus reverse transcriptase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Dimerization inhibitors of HIV-1 reverse transcriptase, protease and integrase: a single mode of inhibition for the three HIV enzymes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

A peptide inhibitor of HIV-1 assembly in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Dimerization kinetics of HIV-1 and HIV-2 reverse transcriptase: a two step process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

The thumb domain of the P51-subunit is essential for activation of HIV reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Insight into the mechanism of a peptide inhibitor of HIV reverse transcriptase dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Effects of efavirenz binding on the subunit equilibria of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Destabilization of the HIV-1 reverse transcriptase dimer upon interaction with N-acyl hydrazone inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

A new potent HIV-1 reverse transcriptase inhibitor. A synthetic peptide derived from the interface subunit domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Nucleotide sequence of the AIDS virus, LAV

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

p66 Trp24 and Phe61 are essential for accurate association of HIV-1 reverse transcriptase with primer/template

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Inhibition of HIV-1 replication by cell-penetrating peptides binding Rev.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

A non-covalent peptide-based strategy for protein and peptide nucleic acid transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

A peptide carrier for the delivery of biologically active proteins into mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Substitutions at Phe61 in the beta3-beta4 hairpin of HIV-1 reverse transcriptase reveal a role for the Fingers subdomain in strand displacement DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Conformational stability of dimeric HIV-1 and HIV-2 reverse transcriptases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

Protein-protein interactions of HIV-1 reverse transcriptase: implication of central and C-terminal regions in subunit binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802199200

21 January 2018

Identifiers

DOI

10.1074/JBC.M802199200

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21 December 2017

PubMed ID

18952602

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21 December 2017