Selective blockade of PGE2 EP1 receptor protects brain against experimental ischemia and excitotoxicity, and hippocampal slice cultures against oxygen-glucose deprivation. (Q46202876)

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English	Selective blockade of PGE2 EP1 receptor protects brain against experimental ischemia and excitotoxicity, and hippocampal slice cultures against oxygen-glucose deprivation.	scientific article

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18 January 2020

Selective blockade of PGE2 EP1 receptor protects brain against experimental ischemia and excitotoxicity, and hippocampal slice cultures against oxygen-glucose deprivation (English)

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18 January 2020

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18 January 2020

author name string

Abdullah Shafique Ahmad

1

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18 January 2020

Yun Tai Yun

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18 January 2020

Muzamil Ahmad

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18 January 2020

Takayuki Maruyama

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18 January 2020

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1 December 2008

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18 January 2020

Neurotoxicity Research

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18 January 2020

14

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18 January 2020

4

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18 January 2020

343-351

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18 January 2020

https://scigraph.springernature.com/pub.10.1007/bf03033858

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The neuroprotective effect of prostaglandin E2 EP1 receptor inhibition has a wide therapeutic window, is sustained in time and is not sexually dimorphic.

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Neuroprotection by PGE2 receptor EP1 inhibition involves the PTEN/AKT pathway

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Effects of EP1 receptor on cerebral blood flow in the middle cerebral artery occlusion model of stroke in mice

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Stimulation of PGE receptors EP2 and EP4 protects cultured neurons against oxidative stress and cell death following beta-amyloid exposure

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Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial

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Prostaglandin E2 as a mediator of fever: the role of prostaglandin E (EP) receptors

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Inhibition of human glioma cell growth by a PHS-2 inhibitor, NS398, and a prostaglandin E receptor subtype EP1-selective antagonist, SC51089.

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N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx

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The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure

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3 July 2018

Inhibitory effect of a prostaglandin E receptor subtype EP(1) selective antagonist, ONO-8713, on development of azoxymethane-induced aberrant crypt foci in mice

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Prostanoid receptors: structures, properties, and functions

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15 August 2018

Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

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A simple method for organotypic cultures of nervous tissue

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3 July 2018

Stimulation of prostaglandin EP2 receptors prevents NMDA-induced excitotoxicity.

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15 August 2018

Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity

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1-hydroxyPGE reduces infarction volume in mouse transient cerebral ischemia

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15 August 2018

Prostaglandin E2 deteriorates N-methyl-D-aspartate receptor-mediated cytotoxicity possibly by activating EP2 receptors in cultured cortical neurons

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15 August 2018

Prostaglandin EP1 receptor contributes to excitotoxicity and focal ischemic brain damage

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The dual role of prostaglandin E(2) in excitotoxicity and preconditioning-induced neuroprotection

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Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study

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Role of prostaglandin receptor subtype EP1 in prostaglandin E2-induced nociceptive transmission in the rat spinal dorsal horn

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15 August 2018

Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.

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Neuronal overexpression of cyclooxygenase-2 increases cerebral infarction.

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15 August 2018

Prostaglandin (PG) FP and EP1 receptors mediate PGF2alpha and PGE2 regulation of interleukin-1beta expression in Leydig cell progenitors

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15 August 2018

A prostaglandin E2 receptor subtype EP1 receptor antagonist (ONO-8711) reduces hyperalgesia, allodynia, and c-fos gene expression in rats with chronic nerve constriction

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15 August 2018

Oxidative burst and NO generation as initial response to ischemia in flow-adapted endothelial cells

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15 August 2018

PGE2 receptor subtype EP1 antagonist may inhibit central interleukin-1beta-induced fever in rats.

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The cyclooxygenase-2 inhibitor NS-398 ameliorates ischemic brain injury in wild-type mice but not in mice with deletion of the inducible nitric oxide synthase gene

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12 December 2020

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Involvement of glutamate receptors in allodynia induced by prostaglandins E2 and F2α injected into conscious mice

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Cyclooxygenase-2 induction in cerebral cortex: an intracellular response to synaptic excitation

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12 December 2020

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The effects of intrathecal administration of an antagonist for prostaglandin E receptor subtype EP(1) on mechanical and thermal hyperalgesia in a rat model of postoperative pain

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12 December 2020

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Identifiers

10.1007/BF03033858

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18 January 2020

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18 January 2020

1 reference

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18 January 2020

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