Altered cell surface expression and signaling of leptin receptors containing the fatty mutation (Q46202425)

20 December 2017

title

Altered cell surface expression and signaling of leptin receptors containing the fatty mutation (English)

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20 December 2017

author name string

Crouse JA

1

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20 December 2017

Elliott GE

2

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20 December 2017

Burgess TL

3

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20 December 2017

Chiu L

4

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20 December 2017

Bennett L

5

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20 December 2017

Moore J

6

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20 December 2017

Nicolson M

7

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20 December 2017

Pacifici RE

8

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20 December 2017

language of work or name

English

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publication date

1 July 1998

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20 December 2017

Journal of Biological Chemistry

published in

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20 December 2017

volume

273

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20 December 2017

page(s)

18365-18373

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20 December 2017

issue

29

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20 December 2017

Positional cloning of the mouse obese gene and its human homologue

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Weight-reducing effects of the plasma protein encoded by the obese gene

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Identification and expression cloning of a leptin receptor, OB-R

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

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Abnormal splicing of the leptin receptor in diabetic mice

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Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

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Defective STAT signaling by the leptin receptor in diabetic mice

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Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization

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Cloning and characterization of a human leptin receptor using a biologically active leptin immunoadhesin

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Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

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Leptin enters the brain by a saturable system independent of insulin

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Leptin receptor missense mutation in the fatty Zucker rat.

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Phenotype-linked amino acid alteration in leptin receptor cDNA from Zucker fatty (fa/fa) rat.

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Substitution at codon 269 (glutamine --> proline) of the leptin receptor (OB-R) cDNA is the only mutation found in the Zucker fatty (fa/fa) rat.

21 January 2018

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Molecular cloning of rat leptin receptor isoform complementary DNAs--identification of a missense mutation in Zucker fatty (fa/fa) rats

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Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat.

21 January 2018

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Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells

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Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

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Constitutive and impaired signaling of leptin receptors containing the Gln --> Pro extracellular domain fatty mutation

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Expression cloning of the murine erythropoietin receptor

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Expression of human class II major histocompatibility complex antigens using retrovirus vectors

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Quality control in the secretory pathway

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ER quality control: the cytoplasmic connection

21 January 2018

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OB protein binds specifically to the choroid plexus of mice and rats

21 January 2018

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21 January 2018

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Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding

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Defective membrane expression of human growth hormone (GH) receptor causes Laron-type GH insensitivity syndrome

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Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.29.18365

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20 December 2017

PubMed ID

9660803

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20 December 2017