PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway (Q46158612)

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scientific article published on 16 January 2009

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English	PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway	scientific article published on 16 January 2009

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scholarly article

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway (English)

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

reperfusion injury

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Claes-Göran Ostenson

3

object named as

Claes-Göran Ostenson

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object named as

John Pernow

6

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author name string

Aliaksandr A Bulhak

1

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

Christian Jung

2

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

Claes-Göran Ostenson

3

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

Jon O Lundberg

4

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

Per-Ove Sjöquist

5

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

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publication date

16 January 2009

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

American Journal of Physiology Heart and Circulatory Physiology

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

296

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

3

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

H719-27

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

Peroxisome proliferator-activated receptors in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation

1 reference

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WY-14643 and 9- cis-retinoic acid induce IRS-2/PI 3-kinase signalling pathway and increase glucose transport in human skeletal muscle cells: differential effect in myotubes from healthy subjects and Type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Protection against myocardial ischaemia/reperfusion injury by PPAR-alpha activation is related to production of nitric oxide and endothelin-1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Endothelial dysfunction and salt-sensitive hypertension in spontaneously diabetic Goto-Kakizaki rats

1 reference

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21 January 2018

Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1 reference

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21 January 2018

Early phase acute myocardial infarct size quantification: Validation of the triphenyl tetrazolium chloride tissue enzyme staining technique

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Peroxisome proliferator-activated receptor alpha agonists increase nitric oxide synthase expression in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Bezafibrate has an antioxidant effect: peroxisome proliferator-activated receptor alpha is associated with Cu2+, Zn2+-superoxide dismutase in the liver

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Expression of peroxisome proliferator-activated receptor alpha (PPAR alpha) in primary cultures of human vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Myocardial reperfusion injury in neuronal nitric oxide synthase deficient mice.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

The PI3-K/Akt pathway: roles related to alterations in vasomotor responses in diabetic models

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Coronary heart disease incidence in NIDDM patients in the Helsinki Heart Study

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Islet gene expression and function in type 2 diabetes; studies in the Goto-Kakizaki rat and humans

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Regulation of p85alpha phosphatidylinositol-3-kinase expression by peroxisome proliferator-activated receptors (PPARs) in human muscle cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT).

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

The role of phosphoinositide 3-kinase in insulin signalling

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Therapeutic roles of peroxisome proliferator-activated receptor agonists

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Preconditioning the diabetic heart: the importance of Akt phosphorylation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Effects of bezafibrate on the expression of endothelial nitric oxide synthase gene and its mechanisms in cultured bovine endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Activation of peroxisome proliferator-activated receptor-alpha protects the heart from ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Insulin action and insulin resistance in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00394.2008

21 January 2018

Identifiers

10.1152/AJPHEART.00394.2008

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

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https://api.fatcat.wiki/v0/release/zlicwzyp3zbefdsxjmlu5slkxy

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1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19151258

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