Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord. (Q46139008)

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scientific article published in September 2006

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English	Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord.	scientific article published in September 2006

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30 December 2019

Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord (English)

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30 December 2019

Mark H. Tuszynski

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Mark H Tuszynski

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30 December 2019

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Laura Taylor

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Leonard Jones

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1 September 2006

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Journal of Neuroscience

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9713-9721

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30 December 2019

describes a project that uses

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11 June 2022

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Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function.

1 reference

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12 December 2020

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Development and specification of muscle sensory neurons

1 reference

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12 December 2020

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Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

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NT-3 promotes growth of lesioned adult rat sensory axons ascending in the dorsal columns of the spinal cord.

1 reference

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12 December 2020

based on heuristic

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Functional regeneration of sensory axons into the adult spinal cord.

1 reference

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12 December 2020

based on heuristic

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Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function

1 reference

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12 December 2020

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Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor

1 reference

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12 December 2020

based on heuristic

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Neurotrophins are required for nerve growth during development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Leukemia inhibitory factor determines the growth status of injured adult sensory neurons

1 reference

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12 December 2020

based on heuristic

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Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats

1 reference

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12 December 2020

based on heuristic

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Functional regeneration of chronically injured sensory afferents into adult spinal cord after neurotrophin gene therapy.

1 reference

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12 December 2020

based on heuristic

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Axonal regeneration and functional recovery after complete spinal cord transection in rats by delayed treatment with transplants and neurotrophins.

1 reference

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12 December 2020

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Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Promoting axonal regeneration in the central nervous system by enhancing the cell body response to axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

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Characterization of lentiviral vector-mediated gene transfer in adult mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Developmentally Regulated Expression of HDNF/NT-3 mRNA in Rat Spinal Cord Motoneurons and Expression of BDNF mRNA in Embryonic Dorsal Root Ganglion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Spontaneous and augmented growth of axons in the primate spinal cord: effects of local injury and nerve growth factor-secreting cell grafts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Signaling the pathway to regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Nerve growth factor and semaphorin 3A signaling pathways interact in regulating sensory neuronal growth cone motility.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Changes in NT-3 and TrkC in the primary visual cortex of developing macaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Neurotrophin-3 is required for appropriate establishment of thalamocortical connections

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-3 expressed in situ induces axonal plasticity in the adult injured spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

False resurrections: distinguishing regenerated from spared axons in the injured central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage-derived factors stimulate optic nerve regeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Regeneration beyond the glial scar

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NT-3 replacement with brain-derived neurotrophic factor redirects vestibular nerve fibers to the cochlea

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

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Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal responses to cellularly delivered NT-4/5 after spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A chemoattractant role for NT-3 in proprioceptive axon guidance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotactic response of nerve fiber elongation to nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-dependent effects of recombinant human NGF on grafted adult adrenal medullary tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of rubrospinal and corticospinal neurons to injury and neurotrophins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axon guidance by diffusible repellants and attractants

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of neurotrophin-3 results in death of spinal sensory neurons and premature differentiation of their precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The trkA receptor mediates growth cone turning toward a localized source of nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limb proprioceptive deficits without neuronal loss in transgenic mice overexpressing neurotrophin-3 in the developing nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute morphogenic and chemotropic effects of neurotrophins on cultured embryonic Xenopus spinal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins as in vitro growth cone guidance molecules for embryonic sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats--similarities to astrocyte grafts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NT-3 delivered by an adenoviral vector induces injured dorsal root axons to regenerate into the spinal cord of adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16988042

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0734-06.2006

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30 December 2019

1 reference

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30 December 2019

1 reference

Europe PubMed Central

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30 December 2019

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