Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus (Q46132315)

19 December 2017

title

Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus (English)

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19 December 2017

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Won-Jin Cho

1

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19 December 2017

Bhanu P Jena

series ordinal

2

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19 December 2017

Aleksandar M Jeremic

series ordinal

3

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19 December 2017

publication date

1 January 2008

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19 December 2017

published in

Methods in Cell Biology

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19 December 2017

volume

90

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19 December 2017

page(s)

267-286

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19 December 2017

Autoinsertion of soluble oligomers of Alzheimer's Abeta(1-42) peptide into cholesterol-containing membranes is accompanied by relocation of the sterol towards the bilayer surface.

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Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

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Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes?

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Diabetes mellitus in Macaca mulatta monkeys is characterised by islet amyloidosis and reduction in beta-cell population.

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Islet amyloid polypeptide forms rigid lipid-protein amyloid fibrils on supported phospholipid bilayers

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Cholesterol and the interaction of proteins with membrane domains.

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Polymorphic Fibrillar Assembly of Human Amylin

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Watching amyloid fibrils grow by time-lapse atomic force microscopy

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Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation

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Full-length rat amylin forms fibrils following substitution of single residues from human amylin

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Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

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Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

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Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology

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7 January 2021

Lipid membranes modulate the structure of islet amyloid polypeptide.

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7 January 2021

Membrane interaction of islet amyloid polypeptide

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Secretion machinery at the cell plasma membrane

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Involvement of water channels in synaptic vesicle swelling

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Calcium drives fusion of SNARE-apposed bilayers

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Energy-dependent disassembly of self-assembled SNARE complex: observation at nanometer resolution using atomic force microscopy

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The Importance of -Cell Failure in the Development and Progression of Type 2 Diabetes

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Phospholipid catalysis of diabetic amyloid assembly

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Conserved and Cooperative Assembly of Membrane-Bound α-Helical States of Islet Amyloid Polypeptide†

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Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy

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Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

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7 January 2021

Small-volume extrusion apparatus for preparation of large, unilamellar vesicles

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Aromatic Interactions Are Not Required for Amyloid Fibril Formation by Islet Amyloid Polypeptide but Do Influence the Rate of Fibril Formation and Fibril Morphology†

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Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins

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Islet amyloid polypeptide (IAPP) and pancreatic islet amyloid deposition in diabetic and non-diabetic patients

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Islet amyloid: phase partitioning and secondary nucleation are central to the mechanism of fibrillogenesis.

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7 January 2021

Aggregation of an amyloidogenic fragment of human islet amyloid polypeptide

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7 January 2021

Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.

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7 January 2021

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7 January 2021

Fiber-dependent amyloid formation as catalysis of an existing reaction pathway

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7 January 2021

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

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7 January 2021

Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

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7 January 2021

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7 January 2021

Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1.

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7 January 2021

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Identifiers

DOI

1 reference

19 December 2017

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19 December 2017