In vivo neuroprotective effect of L-carnitine against oxidative stress in maple syrup urine disease. (Q46129559)

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24 January 2020

title

In vivo neuroprotective effect of L-carnitine against oxidative stress in maple syrup urine disease (English)

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24 January 2020

4

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24 January 2020

author name string

Caroline Mescka

1

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24 January 2020

Tarsila Moraes

2

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24 January 2020

Andrea Rosa

3

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24 January 2020

Bruna Piccoli

5

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24 January 2020

Carlos Jacques

6

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24 January 2020

Giovana Dalazen

7

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24 January 2020

Juliana Coelho

8

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24 January 2020

Marcelo Cortes

9

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24 January 2020

Melaine Terra

10

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24 January 2020

Carmen Regla Vargas

11

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24 January 2020

Carlos S Dutra-Filho

12

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24 January 2020

publication date

5 March 2011

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24 January 2020

published in

Metabolic Brain Disease

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24 January 2020

volume

26

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24 January 2020

issue

1

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24 January 2020

page(s)

21-28

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https://scigraph.springernature.com/pub.10.1007/s11011-011-9238-x

24 January 2020

exact match

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Evidence that oxidative stress is increased in plasma from patients with maple syrup urine disease.

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Oxidative stress in plasma from maple syrup urine disease patients during treatment.

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Induction of oxidative stress in rat brain by the metabolites accumulating in maple syrup urine disease.

21 January 2018

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alpha-keto acids accumulating in maple syrup urine disease stimulate lipid peroxidation and reduce antioxidant defences in cerebral cortex from young rats.

21 January 2018

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Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats.

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A chemically-induced acute model of maple syrup urine disease in rats for neurochemical studies

21 January 2018

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Stimulation of lipid peroxidation in vitro in rat brain by the metabolites accumulating in maple syrup urine disease

21 January 2018

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Antioxidant and antiradical activities of L-carnitine

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Antioxidants: Molecules, medicines, and myths

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Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

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Oxidative stress and neurodegeneration: where are we now?

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The role of carnitine in normal and altered fatty acid metabolism

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Branched chain amino acids induce apoptosis in neural cells without mitochondrial membrane depolarization or cytochrome c release: implications for neurological impairment associated with maple syrup urine disease

21 January 2018

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Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier

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Oxidative stress-mediated macromolecular damage and dwindle in antioxidant status in aged rat brain regions: role of L-carnitine and DL-alpha-lipoic acid

21 January 2018

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Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

21 January 2018

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N-acetylaspartic acid impairs enzymatic antioxidant defenses and enhances hydrogen peroxide concentration in rat brain.

21 January 2018

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Antiradical effects in L-propionyl carnitine protection of the heart against ischemia-reperfusion injury: the possible role of iron chelation

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Reduction of lipid and protein damage in patients with disorders of propionate metabolism under treatment: a possible protective role of L-carnitine supplementation

21 January 2018

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L-carnitine blood levels and oxidative stress in treated phenylketonuric patients

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Free radical-mediated oxidation of free amino acids and amino acid residues in proteins

21 January 2018

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Maple syrup urine disease: interrelations between branched-chain amino-, oxo- and hydroxyacids; implications for treatment; associations with CNS dysmyelination

21 January 2018

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Oxidative damage to proteins: spectrophotometric method for carbonyl assay

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12 December 2020

L-carnitine protects gastric mucosa by decreasing ischemia-reperfusion induced lipid peroxidation.

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Elevation of amino acids in the interstitial space of the rat brain following infusion of large neutral amino and keto acids by microdialysis: alpha-ketoisocaproate infusion

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Inhibition of brain energy metabolism by the branched-chain amino acids accumulating in maple syrup urine disease

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44 Glutathione peroxidase

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Erythrocyte glutathione peroxidase activity and plasma selenium concentration are reduced in maple syrup urine disease patients during treatment

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Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease

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Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease

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Inhibition of brain energy metabolism by the alpha-keto acids accumulating in maple syrup urine disease

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L-Carnitine in the lipid and protein protection against ethanol-induced oxidative stress

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Protein measurement with the Folin phenol reagent

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MAPLE SYRUP URINE DISEASE, WITH PARTICULAR REFERENCE TO DIETOTHERAPY

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12 December 2020