Dysregulation of PINCH signaling in mesial temporal epilepsy (Q46121276)

http://europepmc.org/abstract/MED/27838154

19 December 2017

title

Dysregulation of PINCH signaling in mesial temporal epilepsy (English)

1 reference

http://europepmc.org/abstract/MED/27838154

19 December 2017

author name string

Charles Liu

1

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14 May 2020

Jon Russin

2

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Christianne Heck

3

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Keisuke Kawata

4

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Radhika Adiga

5

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14 May 2020

William Yen

6

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Jonathan Lambert

7

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Benjamin Stear

8

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Meng Law

9

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Yvette Marquez

10

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Peter Crino

11

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David Millett

12

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Dianne Langford

13

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14 May 2020

publication date

9 November 2016

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http://europepmc.org/abstract/MED/27838154

19 December 2017

published in

Journal of Clinical Neuroscience

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14 May 2020

volume

36

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page(s)

43-52

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describes a project that uses

14 May 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6492941/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Integrin-linked kinase and PINCH: partners in regulation of cell-extracellular matrix interaction and signal transduction.

1 reference

12 December 2020

Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats

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12 December 2020

Subacute electrical stimulation of the hippocampus blocks intractable temporal lobe seizures and paroxysmal EEG activities.

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12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

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12 December 2020

Mesial temporal lobe epilepsy: what have we learned?

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12 December 2020

Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells

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A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration

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12 December 2020

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

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12 December 2020

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

1 reference

12 December 2020

Role of integrin-linked kinase in nerve growth factor-stimulated neurite outgrowth

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12 December 2020

Inactivation of Integrin-linked Kinase Induces Aberrant Tau Phosphorylation via Sustained Activation of Glycogen Synthase Kinase 3β in N1E-115 Neuroblastoma Cells

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12 December 2020

Neurochemical remodelling of the hippocampus in human temporal lobe epilepsy.

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12 December 2020

PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival

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ILAE Commission Report. Mesial temporal lobe epilepsy with hippocampal sclerosis.

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The LIM domain: from the cytoskeleton to the nucleus

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The epidemiology of the comorbidity of epilepsy in the general population

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PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes

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PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

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Somatic comorbidity of epilepsy in the general population in Canada

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Accelerated Tau deposition in the brains of individuals infected with human immunodeficiency virus-1 before and after the advent of highly active anti-retroviral therapy.

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Cognitive prognosis in chronic temporal lobe epilepsy.

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The blood-brain barrier and epilepsy

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

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Cognitive decline in temporal lobe epilepsy due to unilateral hippocampal sclerosis.

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Growing old with epilepsy: the neglected issue of cognitive and brain health in aging and elder persons with chronic epilepsy

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Novel expression of PINCH in the central nervous system and its potential as a biomarker for human immunodeficiency virus-associated neurodegeneration.

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Cerebrospinal fluid tau as a marker of neuronal damage after epileptic seizure.

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12 December 2020

Chronic temporal lobe epilepsy: a neurodevelopmental or progressively dementing disease?

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12 December 2020

PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha

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12 December 2020

Neuronal PINCH is regulated by TNF-α and is required for neurite extension.

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12 December 2020

PINCH: More than just an adaptor protein in cellular response

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12 December 2020

Increased CDK5 expression in HIV encephalitis contributes to neurodegeneration via tau phosphorylation and is reversed with Roscovitine

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12 December 2020

Neurofibrillary tangle pathology and Braak staging in chronic epilepsy in relation to traumatic brain injury and hippocampal sclerosis: a post-mortem study

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Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy

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Developing therapeutic approaches to tau, selected kinases, and related neuronal protein targets

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12 December 2020

Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy.

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12 December 2020

PINCH in the cellular stress response to tau-hyperphosphorylation

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12 December 2020

Pathophysiogenesis of mesial temporal lobe epilepsy: is prevention of damage antiepileptogenic?

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12 December 2020

Changes in PINCH levels in the CSF of HIV+ individuals correlate with hpTau and CD4 count

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12 December 2020

Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies.

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12 December 2020

Tau reduction prevents disease in a mouse model of Dravet syndrome

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12 December 2020

Mossy fiber synaptic reorganization in the epileptic human temporal lobe

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12 December 2020

The vulnerability of calretinin-containing hippocampal interneurons to temporal lobe epilepsy

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12 December 2020

Evaluation of serum matrix metalloproteinase-3 as a biomarker for diagnosis of epilepsy.

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12 December 2020

Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections.

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12 December 2020

Risk of Dementia in Patients with Parkinson's Disease, Epilepsy, and Severe Head Trauma: A Register-based Follow-up Study

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12 December 2020

Senile plaques in temporal lobe epilepsy.

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12 December 2020

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

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12 December 2020

Increased apolipoprotein E epsilon 4 in epilepsy with senile plaques.

1 reference

12 December 2020

10.1016/J.JOCN.2016.10.012

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6492941&resulttype=core&format=json

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14 May 2020

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mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6492941&resulttype=core&format=json

14 May 2020

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