Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival (Q46110606)

9 January 2018

title

Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival (English)

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9 January 2018

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acute myeloid leukemia

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adult acute myeloid leukemia

inferred from title

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11

Gerhard Ehninger

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9 January 2018

13

Heyo K Kroemer

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9 January 2018

Gabriele Jedlitschky

6

object named as

Gabriele Jedlitschky

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9 January 2018

Markus Grube

5

object named as

Markus Grube

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9 January 2018

Werner Siegmund

10

object named as

Werner Siegmund

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9 January 2018

author name string

Yanping Guo

1

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9 January 2018

Kathleen Köck

2

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9 January 2018

Christoph A Ritter

3

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9 January 2018

Zhe-Sheng Chen

4

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9 January 2018

Thomas Illmer

7

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9 January 2018

Mary Ayres

8

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9 January 2018

James F Beck

9

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9 January 2018

Varsha Gandhi

12

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9 January 2018

Gary D Kruh

14

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9 January 2018

Markus Schaich

15

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9 January 2018

language of work or name

English

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publication date

24 February 2009

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9 January 2018

published in

Clinical Cancer Research

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9 January 2018

volume

15

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9 January 2018

issue

5

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9 January 2018

page(s)

1762-1769

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9 January 2018

ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance.

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The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

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MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia.

24 May 2018

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Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11)

24 May 2018

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Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: a phase III trial (E2995)

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Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

24 May 2018

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Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart

24 May 2018

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The multidrug resistance-associated protein 3 (MRP3) is associated with a poor outcome in childhood ALL and may account for the worse prognosis in male patients and T-cell immunophenotype

24 May 2018

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MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine

24 May 2018

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Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

24 May 2018

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Response to chemotherapy and expression of the genes encoding the multidrug resistance-associated proteins MRP2, MRP3, MRP4, MRP5, and SMRP in childhood acute myeloid leukemia.

24 May 2018

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In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia

24 May 2018

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Role of MRP4 and MRP5 in biology and chemotherapy

24 May 2018

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Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.

24 May 2018

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MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer

24 May 2018

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Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12.

24 May 2018

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Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine

24 May 2018

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8-Cl-cAMP induces cell cycle-specific apoptosis in human cancer cells

24 May 2018

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8-Cl-adenosine mediated cytotoxicity and sensitization of T-lymphoblastic leukemia cells to TNFalpha-induced apoptosis is via inactivation of NF-kappaB.

24 May 2018

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Mutations in ras proto-oncogenes are associated with lower mdr1 gene expression in adult acute myeloid leukaemia

24 May 2018

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Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells

24 May 2018

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The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides

24 May 2018

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Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

24 May 2018

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The prognostic significance of membrane transport-associated multidrug resistance (MDR) proteins in leukemia

24 May 2018

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Pharmacologic approaches to reversing multidrug resistance.

24 May 2018

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Reversal of resistance to adriamycin by 8-chloro-cyclic AMP in adriamycin-resistant HL-60 leukemia cells is associated with reduction of type I cyclic AMP-dependent protein kinase and cyclic AMP response element-binding protein DNA-binding activitie

24 May 2018

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The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

24 May 2018

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The contribution of blast cell properties to outcome variation in acute myeloblastic leukemia (AML).

24 May 2018

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Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling

24 May 2018

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Site-selective cyclic AMP analogs as new biological tools in growth control, differentiation, and proto-oncogene regulation

24 May 2018

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cGMP-induced differentiation of the promyelocytic cell line HL-60.

24 May 2018

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Inhibition of the self-renewal capacity of blast progenitors from acute myeloblastic leukemia patients by site-selective 8-chloroadenosine 3',5'-cyclic monophosphate

24 May 2018

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The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis

24 May 2018

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The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites

15 August 2018

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MDR1 protein expression is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia.

15 August 2018

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Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia

15 August 2018

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Increased intracellular cAMP renders HL-60 cells resistant to cytotoxicity of taxol.

15 August 2018

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Overexpression of lung-resistance protein and increased P-glycoprotein function in acute myeloid leukaemia cells predict a poor response to chemotherapy and reduced patient survival.

15 August 2018

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Site-selective cAMP analogs at micromolar concentrations induce growth arrest and differentiation of acute promyelocytic, chronic myelocytic, and acute lymphocytic human leukemia cell lines

15 August 2018

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Isolation and antileukemic activity, in mice, of 1-β-d-arabinofuranosylcytosine 5′-phosphate present in synthetic 5′-cytidylic acid

3 November 2018

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12 December 2020

Addition of cyclosporin A to the combination of mitoxantrone and etoposide to overcome resistance to chemotherapy in refractory or relapsing acute myeloid leukaemia: a randomised phase II trial from HOVON, the Dutch-Belgian Haemato-Oncology Working

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12 December 2020

Comparison of spectral karyotyping and conventional cytogenetics in 39 patients with acute myeloid leukemia and myelodysplastic syndrome

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Studies in mouse L-cells on the incorporation of 1-beta-D-arabinofuranosylcytosine into DNA and on inhibition of DNA polymerase by 1-beta-D-arabinofuranosylcytosine 5'-triphosphate

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12 December 2020

P-glycoprotein expression on acute myeloid leukaemia blast cells at diagnosis predicts response to chemotherapy and survival

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12 December 2020

Expression of multidrug resistance-associated proteins predicts prognosis in childhood and adult acute lymphoblastic leukemia

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12 December 2020

High-performance liquid chromatography method for the determination and quantitation of arabinosylguanine triphosphate and fludarabine triphosphate in human cells

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Identifiers

DOI

1 reference

9 January 2018

PMCID

5744661

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9 January 2018

PubMed ID

19240178

1 reference

9 January 2018