Enzymatic detoxification of gluten by germinating wheat proteases: implications for new treatment of celiac disease. (Q46057460)

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25 January 2020

title

Enzymatic detoxification of gluten by germinating wheat proteases: implications for new treatment of celiac disease (English)

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25 January 2020

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9

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25 January 2020

Pekka T. Männistö

11

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25 January 2020

13

Markku Mäki

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25 January 2020

2

Jarkko I Venäläinen

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25 January 2020

Kaija Laurila

8

object named as

Kaija Laurila

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25 January 2020

Satumarja M Stenman

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Satumarja M Stenman

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25 January 2020

Katri Kaukinen

12

object named as

Katri Kaukinen

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25 January 2020

author name string

Katri Lindfors

3

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25 January 2020

Seppo Auriola

4

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25 January 2020

Timo Mauriala

5

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25 January 2020

Anu Kaukovirta-Norja

6

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25 January 2020

Anna Jantunen

7

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25 January 2020

Ludvig M Sollid

10

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25 January 2020

language of work or name

English

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publication date

1 January 2009

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25 January 2020

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25 January 2020

volume

41

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25 January 2020

issue

5

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25 January 2020

page(s)

390-400

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Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study

25 January 2020

cites work

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Breakdown of gliadin peptides by intestinal brush borders from coeliac patients

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Structural basis for gluten intolerance in celiac sprue

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In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope.

21 January 2018

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Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease

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Parallels between pathogens and gluten peptides in celiac sprue

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Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3

21 January 2018

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Cyclic and dimeric gluten peptide analogues inhibiting DQ2-mediated antigen presentation in celiac disease.

21 January 2018

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Infliximab in refractory coeliac disease.

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Future therapeutic options for celiac disease

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Inhibition of TGF-β Signaling by IL-15: A New Role for IL-15 in the Loss of Immune Homeostasis in Celiac Disease

21 January 2018

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Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function.

21 January 2018

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The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study

21 January 2018

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Design, synthesis, and evaluation of gluten peptide analogs as selective inhibitors of human tissue transglutaminase

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Transglutaminase 2 inhibitors and their therapeutic role in disease states

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Limited efficiency of prolyl-endopeptidase in the detoxification of gliadin peptides in celiac disease

21 January 2018

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Effect of pretreatment of food gluten with prolyl endopeptidase on gluten-induced malabsorption in celiac sprue

21 January 2018

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Comparative biochemical analysis of three bacterial prolyl endopeptidases: implications for coeliac sprue.

21 January 2018

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Fermentation, purification, formulation, and pharmacological evaluation of a prolyl endopeptidase from Myxococcus xanthus: implications for Celiac Sprue therapy

21 January 2018

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Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease

21 January 2018

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Efficient degradation of gluten by a prolyl endoprotease in a gastrointestinal model: implications for coeliac disease

21 January 2018

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Combination enzyme therapy for gastric digestion of dietary gluten in patients with celiac sprue

21 January 2018

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Growth factor-like activity of gliadin, an alimentary protein: implications for coeliac disease

21 January 2018

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Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease.

21 January 2018

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Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation

21 January 2018

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Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits

21 January 2018

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Glutamine supports recovery from loss of transepithelial resistance and increase of permeability induced by media change in Caco-2 cells

21 January 2018

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Oral proteases: a new approach to managing coeliac disease

21 January 2018

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21 January 2018

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