Increased renal Akt/mTOR and MAPK signaling in type I diabetes in the absence of IGF type 1 receptor activation. (Q46039886)

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26 January 2020

title

Increased renal Akt/mTOR and MAPK signaling in type I diabetes in the absence of IGF type 1 receptor activation (English)

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26 January 2020

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author name string

Daniel Landau

1

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26 January 2020

Renanah Eshet

2

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Yotam Gurman

4

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26 January 2020

Yu Chen

5

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26 January 2020

Ralph Rabkin

6

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Yael Segev

7

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publication date

23 April 2009

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26 January 2020

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volume

36

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issue

1

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26 January 2020

page(s)

126-134

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https://scigraph.springernature.com/pub.10.1007/s12020-009-9190-2

26 January 2020

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cites work

Changes in the growth hormone-IGF-I axis in non-obese diabetic mice

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Importance of raised growth hormone levels in mediating the metabolic derangements of diabetes.

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A growth hormone antagonist protects mice against streptozotocin induced glomerulosclerosis even in the presence of elevated levels of glucose and glycated hemoglobin

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Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

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IGF-1 vs insulin: respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line

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Growth hormone receptor antagonism prevents early renal changes in nonobese diabetic mice

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Reduced expression of insulin receptors in the kidneys of insulin-resistant rats

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Production and characterization of recombinant insulin-like growth factor-I (IGF-I) and potent analogues of IGF-I, with Gly or Arg substituted for Glu 3, following their expression in Escherichia coli as fusion proteins

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Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase

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Systemically but not orogastrically delivered insulin-like growth factor (IGF)-I and long [Arg3]IGF-I stimulates intestinal disaccharidase activity in two age groups of suckling rats

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Expression of insulin-like growth factor binding proteins in the rat kidney: effects of long-term diabetes

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Modulation of growth hormone signal transduction in kidneys of streptozotocin-induced diabetic animals: effect of a growth hormone receptor antagonist.

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy

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An IGF-I antagonist does not inhibit renal fibrosis in the rat following subtotal nephrectomy

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Association of urinary inflammatory markers and renal decline in microalbuminuric type 1 diabetics

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Kinase Activities Associated with mTOR

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Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways

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Autoimmune diabetes induced by the beta-cell toxin STZ. Immunity to the 60-kDa heat shock protein and to insulin.

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Wnt/beta-catenin signaling modulates survival of high glucose-stressed mesangial cells

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Therapeutic potential of insulin-like growth factor-1 in patients with diabetes mellitus.

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Regulation of SOCS-3 expression by leptin and its co-localization with insulin receptor in rat skeletal muscle cells

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Rapamycin prevents early steps of the development of diabetic nephropathy in rats

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New concepts: growth hormone, insulin-like growth factor-I and the kidney

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The type 1 insulin-like growth factor receptor pathway

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Renal hypertrophy in hyperglycemic non-obese diabetic mice is associated with persistent renal accumulation of insulin-like growth factor I.

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A novel somatostatin analogue prevents early renal complications in the nonobese diabetic mouse

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Janus tyrosine kinases and signal transducers and activators of transcription regulate critical functions of T cells in allograft rejection and transplantation tolerance

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Identification of the glomerular podocyte as a target for growth hormone action

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Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-1

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12 December 2020

Differential expression of renal growth hormone receptor and its binding protein in experimental diabetes mellitus

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12 December 2020

Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy.

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Glomerular hyperfiltration in insulin-dependent diabetes mellitus is correlated with enhanced growth hormone secretion.

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Is there really good news about pandemic diabetic nephropathy?

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Autocrine activation of the IGF-I signaling pathway in mesangial cells isolated from diabetic NOD mice

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S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover

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The effect of growth hormone on the development of diabetic kidney disease in rats

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12 December 2020

10.1007/S12020-009-9190-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19387875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

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