Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice. (Q45877031)

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6 January 2020

title

Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice (English)

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6 January 2020

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1

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Tura Ferre

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Fatima Bosch

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author name string

I Elias

2

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V Rotter Sopasakis

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I Nagaev

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C X Andersson

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J Agudo

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J Ruberte

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U Smith

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publication date

24 April 2008

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6 January 2020

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6 January 2020

volume

51

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issue

7

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page(s)

1306-1316

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https://scigraph.springernature.com/pub.10.1007/s00125-008-0998-8

6 January 2020

exact match

0 references

cites work

A method to quantify glucose utilization in vivo in skeletal muscle and white adipose tissue of the anaesthetized rat.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-008-0998-8

Insulin-stimulated glucose transport in muscle. Evidence for a protein-kinase-C-dependent component which is unaltered in insulin-resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-008-0998-8

Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-008-0998-8

Muscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-008-0998-8

Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-008-0998-8

Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk

21 January 2018

1 reference

12 December 2020

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

1 reference

12 December 2020

Metabolic effects of interleukin-6 in human splanchnic and adipose tissue

1 reference

12 December 2020

Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin 6 in cancer cachexia

1 reference

12 December 2020

Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase -- increased expression with reduced muscle damage

1 reference

12 December 2020

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

1 reference

12 December 2020

IL-6 signal transduction and its physiological roles: the signal orchestration model

1 reference

12 December 2020

Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver

1 reference

12 December 2020

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

1 reference

12 December 2020

Interleukin-6 induces cellular insulin resistance in hepatocytes

1 reference

12 December 2020

Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro

1 reference

12 December 2020

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

1 reference

12 December 2020

Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo.

1 reference

12 December 2020

Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity

1 reference

12 December 2020

Short-term infusion of interleukin-6 does not induce insulin resistance in vivo or impair insulin signalling in rats

1 reference

12 December 2020

Plasma interleukin-6 levels are independently associated with insulin secretion in a cohort of Italian-Caucasian nondiabetic subjects.

1 reference

12 December 2020

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

1 reference

12 December 2020

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

1 reference

12 December 2020

Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone.

1 reference

12 December 2020

Glucose ingestion attenuates interleukin-6 release from contracting skeletal muscle in humans

1 reference

12 December 2020

Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness.

1 reference

12 December 2020

5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways

1 reference

12 December 2020

Muscle-derived interleukin-6: possible biological effects

1 reference

12 December 2020

Interleukin-6 and diabetes: the good, the bad, or the indifferent?

1 reference

12 December 2020

Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver

1 reference

12 December 2020

Interleukin-6 Regulates Human Adipose Tissue Lipid Metabolism and Leptin Productionin Vitro

1 reference

12 December 2020

C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance.

1 reference

12 December 2020

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

1 reference

12 December 2020

Intracerebroventricular interleukin-6 treatment decreases body fat in rats

1 reference

12 December 2020

Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes

1 reference

12 December 2020

Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro

1 reference

12 December 2020

Recombinant human interleukin-6 infusion during low-intensity exercise does not enhance whole body lipolysis or fat oxidation in humans

1 reference

12 December 2020

Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser473 of Akt.

1 reference

12 December 2020

IL-6 protects pancreatic islet beta cells from pro-inflammatory cytokines-induced cell death and functional impairment in vitro and in vivo

1 reference

12 December 2020

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

1 reference

12 December 2020

Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts

1 reference

12 December 2020

Interleukin-6-deficient mice develop mature-onset obesity

1 reference

12 December 2020

Interleukin-6 increases insulin secretion and preproinsulin mRNA expression via Ca2+-dependent mechanism

1 reference

12 December 2020

Evidence for the involvement of interleukin 6 in experimental cancer cachexia

1 reference

12 December 2020

Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes

1 reference

12 December 2020

Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes

1 reference

12 December 2020

The paradigm of IL-6: from basic science to medicine

1 reference

12 December 2020

AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise

1 reference

12 December 2020

High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator.

1 reference

12 December 2020

Signaling Specificity of Interleukin-6 Action on Glucose and Lipid Metabolism in Skeletal Muscle

1 reference

12 December 2020

Muscle-derived interleukin-6: mechanisms for activation and possible biological roles

1 reference

12 December 2020

10.1007/S00125-008-0998-8

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18437347%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 January 2020

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