Long-term therapeutic levels of human alpha-1 antitrypsin in plasma after hydrodynamic injection of nonviral DNA. (Q45864764)

17 December 2017

title

Long-term therapeutic levels of human alpha-1 antitrypsin in plasma after hydrodynamic injection of nonviral DNA. (English)

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17 December 2017

author name string

Aliño SF

series ordinal

1

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17 December 2017

Crespo A

series ordinal

2

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17 December 2017

Dasí F

series ordinal

3

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17 December 2017

publication date

1 September 2003

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

10

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17 December 2017

issue

19

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17 December 2017

page(s)

1672-1679

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302065

exact match

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cites work

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Clonal gene therapy: transplanted mouse fibroblast clones express human alpha 1-antitrypsin gene in vivo

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Expression of human alpha 1-antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes

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High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

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High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

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Long-term expression of human alpha1-antitrypsin gene in mouse liver achieved by intravenous administration of plasmid DNA using a hydrodynamics-based procedure

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Asialofetuin liposome-mediated human alpha1-antitrypsin gene transfer in vivo results in stationary long-term gene expression

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Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302065

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17 December 2017

Dimensions Publication ID

0 references

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17 December 2017