Impaired Innate Host Defense Causes Susceptibility to Respiratory Virus Infections in Cystic Fibrosis (Q45723562)

15 December 2017

Impaired Innate Host Defense Causes Susceptibility to Respiratory Virus Infections in Cystic Fibrosis (English)

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3 January 2024

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3 January 2024

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Bryan R. G. Williams

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3 January 2024

author name string

Shuo Zheng

1

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15 December 2017

Suresh Choudhary

3

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15 December 2017

Tannishia Goggans

5

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15 December 2017

Roger Slee

6

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15 December 2017

Joseph Pilewski

8

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15 December 2017

Bishnu P. De

2

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3 January 2024

Suzy A. A. Comhair

4

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3 January 2024

S. Jaharul Haque

9

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3 January 2024

Serpil C. Erzurum

10

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3 January 2024

language of work or name

English

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publication date

1 May 2003

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full work available at URL

15 December 2017

http://www.cell.com/article/S1074761303001146/pdf

file format

Portable Document Format

online access status

open access

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https://api.elsevier.com/content/article/PII:S1074761303001146?httpAccept=text/xml

3 January 2024

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https://api.elsevier.com/content/article/PII:S1074761303001146?httpAccept=text/plain

3 January 2024

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https://api.crossref.org/works/10.1016/S1074-7613(03)00114-6

3 January 2024

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15 December 2017

18

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15 December 2017

619-630

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15 December 2017

5

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Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis.

15 December 2017

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Generation of cAMP-Activated Chloride Currents by Expression of CFTR

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Degradation of STAT1 and STAT2 by the V proteins of simian virus 5 and human parainfluenza virus type 2, respectively: consequences for virus replication in the presence of alpha/beta and gamma interferons

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Severe viral respiratory infections in infants with cystic fibrosis.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Proteomic method identifies proteins nitrated in vivo during inflammatory challenge

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Initial and innate responses to viral infections--pattern setting in immunity or disease

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Interferon action against human parainfluenza virus type 3: involvement of a novel antiviral pathway in the inhibition of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Evidence for antiviral effect of nitric oxide. Inhibition of herpes simplex virus type 1 replication

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Cellular protein kinase C isoform zeta regulates human parainfluenza virus type 3 replication

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Role of NH(2)- and COOH-terminal domains of the P protein of human parainfluenza virus type 3 in transcription and replication

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

2-5A-dependent RNase molecules dimerize during activation by 2-5A.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Exhaled nitric oxide is reduced in infants with cystic fibrosis

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

In vivo antioxidant gene expression in human airway epithelium of normal individuals exposed to 100% O2

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Protection of human endothelial cells from oxidant injury by adenovirus-mediated transfer of the human catalase cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

A critical role for inducible nitric oxide synthase in host survival following coxsackievirus B4 infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Human parainfluenza virus type 3 up-regulates major histocompatibility complex class I and II expression on respiratory epithelial cells: involvement of a STAT1- and CIITA-independent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

A Specific Isozyme of 2′-5′ Oligoadenylate Synthetase Is a Dual Function Proapoptotic Protein of the Bcl-2 Family

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

The interferon antiviral response: from viral invasion to evasion

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Effects of viral lower respiratory tract infection on lung function in infants with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Effects of acute viral respiratory tract infections in patients with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Activation of NF-kappaB by double-stranded RNA (dsRNA) in the absence of protein kinase R and RNase L demonstrates the existence of two separate dsRNA-triggered antiviral programs

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Virus interference. II. Some properties of interferon

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Requirement for transcription factor IRF-1 in NO synthase induction in macrophages.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Partial impairment of cytokine responses in Tyk2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Inhibition of viral replication by nitric oxide and its reversal by ferrous sulfate and tricarboxylic acid cycle metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Identification of the cystic fibrosis gene: genetic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Innate immune responses to cytomegalovirus infection in the developing mouse brain and their evasion by virus-infected neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Inactivation of ribonucleotide reductase by nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

High density synthetic oligonucleotide arrays

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Expression of IL-6, IL-8, and RANTES on human bronchial epithelial cells, NCI-H292, induced by influenza virus A.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Role of nitric oxide synthase type 2 in acute infection with murine cytomegalovirus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Respiratory infections in cystic fibrosis patients caused by virus, chlamydia and mycoplasma--possible synergism with Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Identification of the cystic fibrosis gene: chromosome walking and jumping

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

An antiviral mechanism of nitric oxide: inhibition of a viral protease.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Lethal H5N1 influenza viruses escape host anti-viral cytokine responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Structure and function of the CFTR chloride channel

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

How cells respond to interferons

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Cystic fibrosis transmembrane conductance regulator-dependent regulation of epithelial inducible nitric oxide synthase expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Central Role of Double-Stranded RNA-Activated Protein Kinase in Microbial Induction of Nitric Oxide Synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Association of respiratory viral infections with pulmonary deterioration in patients with cystic fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Yet another role for the cystic fibrosis transmembrane conductance regulator

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Nitric oxide inhibition of coxsackievirus replication in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Rhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900114-6

7 January 2021

Role of cellular actin in human parainfluenza virus type 3 genome transcription

12

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https://api.crossref.org/works/10.1016/S1074-7613(03)00114-6

Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites:implications in inflammation

3 January 2024

29

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https://api.crossref.org/works/10.1016/S1074-7613(03)00114-6

Human and mouse Mx proteins inhibit different steps of the influenza virus multiplication cycle

3 January 2024

55

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https://api.crossref.org/works/10.1016/S1074-7613(03)00114-6

Does nitric oxide play a critical role in viral infections?

3 January 2024

57

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https://api.crossref.org/works/10.1016/S1074-7613(03)00114-6

3 January 2024

Identifiers

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15 December 2017

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