Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease (Q45305307)

11 December 2017

Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease (English)

1 reference

11 December 2017

0 references

0 references

6

Gary Lynch

1 reference

11 December 2017

Danielle A Simmons

1

1 reference

11 December 2017

Malcolm Casale

2

1 reference

11 December 2017

Betzi Alcon

3

1 reference

11 December 2017

Nha Pham

4

1 reference

11 December 2017

Natasha Narayan

5

1 reference

11 December 2017

1 August 2007

1 reference

11 December 2017

1 reference

11 December 2017

55

1 reference

11 December 2017

10

1 reference

11 December 2017

1074-1084

1 reference

Early and progressive accumulation of reactive microglia in the Huntington disease brain

11 December 2017

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

MR evaluation of age-related increase of brain iron in young adult and older normal males

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Increased basal ganglia iron levels in Huntington disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Brain ferritin iron may influence age- and gender-related risks of neurodegeneration.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Mitochondrial dysfunction in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron status and neural functioning

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Brain iron pathways and their relevance to Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Role of iron in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Serum ferritin deficiency in Huntington's disease patients

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative stress in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Normal huntingtin function: an alternative approach to Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron regulation in the brain: histochemical, biochemical, and molecular considerations

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

A histochemical study of iron, transferrin, and ferritin in Alzheimer's diseased brains.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Isoforms of ferritin have a specific cellular distribution in the brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Amyloid-beta metal interaction and metal chelation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Damage to the DNA bases in mammalian chromatin by hydrogen peroxide in the presence of ferric and cupric ions

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

In vitro studies of ferritin iron release and neurotoxicity.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Relative resistance of striatal neurons containing calbindin or parvalbumin to quinolinic acid-mediated excitotoxicity compared to other striatal neuron types.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Huntingtin inclusion bodies are iron-dependent centers of oxidative events.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Regional distribution of iron, transferrin, ferritin, and oxidatively-modified proteins in young and aged Fischer 344 rat brains.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Ferritin is a component of the neuritic (senile) plaque in Alzheimer dementia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative stress and inflammation in Parkinson's disease: is there a causal link?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

G proteins and small GTPases: distant relatives keep in touch.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Expression of ferritin protein and subunit mRNAs in normal and iron deficient rat brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Pathological relationships between microglial cell activity and tau and amyloid beta protein in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Ascorbic acid and iron metabolism: alterations in lysosomal function

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Genetic contributions to Parkinson's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Ionized calcium-binding adapter molecule 1 immunoreactive cells change in the gerbil hippocampal CA1 region after ischemia/reperfusion.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglia-specific localisation of a novel calcium binding protein, Iba1

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Brain iron and ferritin in Parkinson's and Alzheimer's diseases.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative stress in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Macrophage/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma -dependent pathway

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Ferritin immunohistochemistry as a marker for microglia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Does cellular iron dysregulation play a causative role in Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglia in health and disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

The roles of iron in health and disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Theta stimulation polymerizes actin in dendritic spines of hippocampus.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglia density decreases with age in a mouse model of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Oxidation-induced ferritin turnover in microglial cells: role of proteasome.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Serum iron, total iron binding capacity and ferritin in early Huntington disease patients

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Decreased neuronal and increased oligodendroglial densities in Huntington's disease caudate nucleus

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Control of glial immune function by neurons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron, neuroinflammation, and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

The specific vulnerability of the substantia nigra to MPTP is related to the presence of transition metals

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Overactivation of LPS-stimulated microglial cells by co-cultured neurons or neuron-conditioned medium.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Cellular iron metabolism.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Widespread expression of Huntington's disease gene (IT15) protein product

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Temporal variation of hydroxyl radical generation and 8-hydroxy-2'-deoxyguanosine formation by coarse and fine particulate matter

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Dystrophic microglia in the aging human brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Microglial senescence: does the brain's immune system have an expiration date?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Reactive microgliosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Iron uptake by glial cells.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Imaging microglial activation in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

The ubiquitin-proteasome system in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Neuropathological classification of Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Activated microglia cause superoxide-mediated release of iron from ferritin

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Activated microglia cause iron-dependent lipid peroxidation in the presence of ferritin.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Depletion of wild-type huntingtin in mouse models of neurologic diseases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20526

7 January 2021

Identifiers

DOI

10.1002/GLIA.20526

1 reference

11 December 2017

1 reference