Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity. (Q45305295)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Carlos A. Saura

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jordi Alberch

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jorge Valero

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Arnaldo Parra-Damas

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

M Puigdellívol

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

O Carretón

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

P Paoletti

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

S Ginés

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

publication date

24 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

1203-1216

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116937%20AND%20SRC:MED&resulttype=core&format=json

Evidence for specific cognitive deficits in preclinical Huntington's disease.

17 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

The molecular biology of memory storage: a dialogue between genes and synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Coregulator codes of transcriptional regulation by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Phosphorylated CREB binds specifically to the nuclear protein CBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

CBP and p300: HATs for different occasions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

The transcriptional coactivators p300 and CBP are histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

CREB-binding protein and p300 in transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

CREB binding protein is required for both short-term and long-term memory formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Histone deacetylase inhibitors reduce polyglutamine toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Executive and mnemonic functions in early Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Neuroanatomic profile of polyglutamine immunoreactivity in Huntington disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Profile of cognitive progression in early Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Subtle changes among presymptomatic carriers of the Huntington's disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Confirmation of subtle motor changes among presymptomatic carriers of the Huntington disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation--a longitudinal follow-up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Functional imaging in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Cortical dysfunction in patients with Huntington's disease during working memory performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Molecular and cellular mechanisms of memory allocation in neuronetworks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

beta-Amyloid disrupts activity-dependent gene transcription required for memory through the CREB coactivator CRTC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Rubinstein-Taybi syndrome: molecular findings and therapeutic approaches to improve cognitive dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Hippocampus development and function: role of epigenetic factors and implications for cognitive disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Brain plasticity, memory and neurological disorders: an epigenetic perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Epigenetic regulation in psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Regulation of histone acetylation during memory formation in the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Epigenetic mechanisms in memory formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Modulation of long-term memory for object recognition via HDAC inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Recovery of learning and memory is associated with chromatin remodelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Targeting the correct HDAC(s) to treat cognitive disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Qualitatively different modes of perirhinal-hippocampal engagement when rats explore novel vs. familiar objects as revealed by c-Fos imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Impaired interleukin-1beta and c-Fos expression in the hippocampus is associated with a spatial memory deficit in P2X(7) receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Knock-down of PQBP1 impairs anxiety-related cognition in mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR552