Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes (Q45289091)

11 December 2017

Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes (English)

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11 December 2017

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7

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16 May 2020

Yijuang Chern

8

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16 May 2020

author name string

Szu-Yi Chou

1

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16 May 2020

Ju-Yun Weng

2

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16 May 2020

Hsing-Lin Lai

3

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16 May 2020

Fang Liao

4

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16 May 2020

Synthia H Sun

5

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16 May 2020

Pang-Hsien Tu

6

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16 May 2020

language of work or name

English

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publication date

1 March 2008

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11 December 2017

Journal of Neuroscience

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16 May 2020

volume

28

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issue

13

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16 May 2020

page(s)

3277-3290

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Expression of the Huntington's disease gene is regulated in astrocytes in the arcuate nucleus of the hypothalamus of postpartum rats.

16 May 2020

cites work

1 reference

12 December 2020

An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta

1 reference

12 December 2020

Interleukin-1beta induction of the chemokine RANTES promoter in the human astrocytoma line CH235 requires both constitutive and inducible transcription factors

1 reference

12 December 2020

Progressive depletion of complexin II in a transgenic mouse model of Huntington's disease

1 reference

12 December 2020

Neurological abnormalities in a knock-in mouse model of Huntington's disease

1 reference

12 December 2020

RANTES promotes growth and survival of human first-trimester forebrain astrocytes

1 reference

12 December 2020

Neuroprotective role for the p50 subunit of NF-kappaB in an experimental model of Huntington's disease

1 reference

12 December 2020

RANTES: a versatile and controversial chemokine

1 reference

12 December 2020

Fusion protein vesicle-associated membrane protein 2 is implicated in IFN-gamma-induced piecemeal degranulation in human eosinophils from atopic individuals

1 reference

12 December 2020

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

12 December 2020

The role of glial cells in Parkinson's disease

1 reference

12 December 2020

The molecular bases of Alzheimer's disease and other neurodegenerative disorders

1 reference

12 December 2020

Impaired glutamate uptake in the R6 Huntington's disease transgenic mice.

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12 December 2020

Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.

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12 December 2020

Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice

1 reference

12 December 2020

IL-16 promotes leukotriene C(4) and IL-4 release from human eosinophils via CD4- and autocrine CCR3-chemokine-mediated signaling

1 reference

12 December 2020

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

1 reference

12 December 2020

Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation

1 reference

12 December 2020

Essential role of cAMP-response element-binding protein activation by A2A adenosine receptors in rescuing the nerve growth factor-induced neurite outgrowth impaired by blockage of the MAPK cascade

1 reference

12 December 2020

The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor

1 reference

12 December 2020

Regulation of RANTES promoter activation in alveolar epithelial cells after cytokine stimulation

1 reference

12 December 2020

The c-Fes protein-tyrosine kinase accelerates NGF-induced differentiation of PC12 cells through a PI3K-dependent mechanism

1 reference

12 December 2020

BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis

1 reference

12 December 2020

Transcriptional abnormalities in Huntington disease

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12 December 2020

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

1 reference

12 December 2020

Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain

1 reference

12 December 2020

Inclusion formation in Huntington's disease R6/2 mouse muscle cultures

1 reference

12 December 2020

Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation

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12 December 2020

Huntingtin-protein interactions and the pathogenesis of Huntington's disease

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12 December 2020

Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments

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12 December 2020

Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice

1 reference

12 December 2020

Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-beta

1 reference

12 December 2020

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

12 December 2020

Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.

1 reference

12 December 2020

Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells

1 reference

12 December 2020

Striatal potassium channel dysfunction in Huntington's disease transgenic mice

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12 December 2020

Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways.

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12 December 2020

Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila.

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12 December 2020

cAMP-response element-binding protein contributes to suppression of the A2A adenosine receptor promoter by mutant Huntingtin with expanded polyglutamine residues

1 reference

12 December 2020

The MAP kinase pathway is upstream of the activation of GSK3beta that enables it to phosphorylate MAP1B and contributes to the stimulation of axon growth.

1 reference

12 December 2020

CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.

1 reference

12 December 2020

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

1 reference

12 December 2020

Astrocytes, from brain glue to communication elements: the revolution continues

1 reference

12 December 2020

G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells.

1 reference

12 December 2020

Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

1 reference

12 December 2020

Induction of RANTES and CCR5 through NF-kappaB activation via MAPK pathway in aged rat gingival tissues

1 reference

12 December 2020

In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets

1 reference

12 December 2020

Brefeldin A and the endocytic pathway. Possible implications for membrane traffic and sorting.

1 reference

12 December 2020

Huntington's disease: intracellular signaling pathways and neuronal death

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12 December 2020

The secretory capacity of a cell depends on the efficiency of endoplasmic reticulum-associated degradation.

1 reference

12 December 2020

Biologically active molecules that reduce polyglutamine aggregation and toxicity

1 reference

12 December 2020

IL-1 beta and TNF-alpha regulation of the adenosine receptor (A2A) expression: differential requirement for NF-kappa B binding to the proximal promoter

1 reference

12 December 2020

Simvastatin down regulates mRNA expression of RANTES and CCR5 in posttransplant renal recipients with hyperlipidemia.

1 reference

12 December 2020

Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism.

1 reference

12 December 2020

Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells.

1 reference

12 December 2020

Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease

1 reference

12 December 2020

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1 reference

12 December 2020

Activation of NF-kappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells

1 reference

12 December 2020

Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

1 reference

12 December 2020

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

12 December 2020

Primary sensory neurons migrate in response to the chemokine RANTES

1 reference

12 December 2020

Huntingtin protein colocalizes with lesions of neurodegenerative diseases: An investigation in Huntington's, Alzheimer's, and Pick's diseases

1 reference

12 December 2020

10.1523/JNEUROSCI.0116-08.2008

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670608&resulttype=core&format=json

16 May 2020

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16 May 2020

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