N (α)-Methylated phenylhistamines exhibit affinity to the hH(4)R-a pharmacological and molecular modelling study (Q45263489)

11 December 2017

N (α)-Methylated phenylhistamines exhibit affinity to the hH(4)R-a pharmacological and molecular modelling study (English)

1 reference

11 December 2017

Hans-Joachim Wittmann

1

1 reference

11 December 2017

Sigurd Elz

2

1 reference

11 December 2017

Roland Seifert

3

1 reference

11 December 2017

Andrea Straber

4

1 reference

11 December 2017

29 July 2011

1 reference

Naunyn-Schmiedeberg's Archives of Pharmacology

11 December 2017

1 reference

11 December 2017

384

1 reference

11 December 2017

3

1 reference

11 December 2017

287-299

1 reference

https://scigraph.springernature.com/pub.10.1007/s00210-011-0671-5

11 December 2017

0 references

cites work

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Location of Trp265 in metarhodopsin II: implications for the activation mechanism of the visual receptor rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Histaprodifens: synthesis, pharmacological in vitro evaluation, and molecular modeling of a new class of highly active and selective histamine H(1)-receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

International Union of Pharmacology. XLVI. G protein-coupled receptor list.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

A selective human H(4)-receptor agonist: (-)-2-cyano-1-methyl-3-[(2R,5R)-5- [1H-imidazol-4(5)-yl]tetrahydrofuran-2-y] methylguanidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

The first potent and selective non-imidazole human histamine H4 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Phenylalanine 169 in the second extracellular loop of the human histamine H4 receptor is responsible for the difference in agonist binding between human and mouse H4 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Point mutations in the second extracellular loop of the histamine H2 receptor do not affect the species-selective activity of guanidine-type agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Crystal structure of opsin in its G-protein-interacting conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

High constitutive activity and a G-protein-independent high-affinity state of the human histamine H(4)-receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Discovery of quinazolines as histamine H4 receptor inverse agonists using a scaffold hopping approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Major advances in the development of histamine H4 receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

GROMACS: fast, flexible, and free

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea pig H1-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

3D-QSAR CoMFA Study to Predict Orientation of Suprahistaprodifens and Phenoprodifens in the Binding-Pocket of Four Histamine H1 -Receptor Species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Calculation of the free energy of solvation for neutral analogs of amino acid side chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The Beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-011-0671-5

Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists.

21 January 2018

1 reference

12 December 2020

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

1 reference

12 December 2020

The histamine H4 receptor as a new therapeutic target for inflammation

1 reference

12 December 2020

Molecular analysis of beta(2)-adrenoceptor coupling to G(s)-, G(i)-, and G(q)-proteins.

1 reference

12 December 2020

Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms

1 reference

12 December 2020

Synthesis and histamine H1 receptor agonist activity of a series of 2-phenylhistamines, 2-heteroarylhistamines, and analogues

1 reference

12 December 2020

Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors

1 reference

12 December 2020

10.1007/S00210-011-0671-5

Identifiers

DOI

1 reference

Dimensions Publication ID

11 December 2017

0 references

1 reference