Effect of mutating the two cysteines required for HBe antigenicity on hepatitis B virus DNA replication and virion secretion. (Q45231487)

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7 January 2020

title

Effect of mutating the two cysteines required for HBe antigenicity on hepatitis B virus DNA replication and virion secretion (English)

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7 January 2020

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7 January 2020

Fabien Zoulim

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author name string

Genie Bang

1

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7 January 2020

Michael Guarnieri

3

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7 January 2020

Shigenobu Kawai

5

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7 January 2020

Jisu Li

6

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7 January 2020

Jack Wands

7

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7 January 2020

Shuping Tong

8

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language of work or name

English

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publication date

1 February 2005

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7 January 2020

volume

332

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issue

1

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7 January 2020

page(s)

216-224

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Sequence variation upstream of precore translation initiation codon reduces hepatitis B virus e antigen production

7 January 2020

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Phylogenetic origin of hepatitis B virus strains with precore C-1858 variant

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Genotype F prevails in HBV infected patients of Hispanic origin in Central America and may carry the precore stop mutant

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Formation of transmembraneous hepatitis B e-antigen by cotranslational in vitro processing of the viral precore protein

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Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B

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Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene

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The encapsidation signal on the hepatitis B virus RNA pregenome forms a stem-loop structure that is critical for its function

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Low-level secretion of human hepatitis B virus virions caused by two independent, naturally occurring mutations (P5T and L60V) in the capsid protein

7 January 2021

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Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal

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Sequence analysis of the hepatitis B virus pre-C region in hepatocellular carcinoma [HCC] and nontumoral liver tissues from HCC patients

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Proteolytic processing of the hepatitis B virus e antigen precursor. Cleavage at two furin consensus sequences

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Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection

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Is a function of the secreted hepatitis B e antigen to induce immunologic tolerance in utero?

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Conserved cysteines of the hepatitis B virus core protein are not required for assembly of replication-competent core particles nor for their envelopment

7 January 2021

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Hepatitis B virus gene function: the precore region targets the core antigen to cellular membranes and causes the secretion of the e antigen

7 January 2021

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Genome replication, virion secretion, and e antigen expression of naturally occurring hepatitis B virus core promoter mutants.

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Mapping of amino acid side chains on the surface of hepatitis B virus capsids required for envelopment and virion formation

7 January 2021

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A new hepatitis B virus variant in a chronic carrier with multiple episodes of viral reactivation and acute hepatitis

7 January 2021

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Biologic properties of hepatitis B viral genomes with mutations in the precore promoter and precore open reading frame

7 January 2021

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Replication of the wild type and a natural hepatitis B virus nucleocapsid promoter variant is differentially regulated by nuclear hormone receptors in cell culture.

7 January 2021

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Active hepatitis B virus replication in the presence of anti-HBe is associated with viral variants containing an inactive pre-C region

7 January 2021

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In vitro replication competence of a cloned hepatitis B virus variant with a nonsense mutation in the distal pre-C region

7 January 2021

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Replication capacities of natural and artificial precore stop codon mutants of hepatitis B virus: relevance of pregenome encapsidation signal

7 January 2021

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Distinct modes of regulation of transcription of hepatitis B virus by the nuclear receptors HNF4alpha and COUP-TF1

7 January 2021

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Regulation of hepatitis B virus core promoter by transcription factors HNF1 and HNF4 and the viral X protein

7 January 2021

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7 January 2021

The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host

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7 January 2021

Hepatitis B virus genotype A rarely circulates as an HBe-minus mutant: possible contribution of a single nucleotide in the precore region.

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7 January 2021

An intramolecular disulfide bridge between Cys-7 and Cys61 determines the structure of the secretory core gene product (e antigen) of hepatitis B virus

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7 January 2021

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7 January 2021

Enrichment of a precore-minus mutant of duck hepatitis B virus in experimental mixed infections

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7 January 2021