Tandospirone activates neuroendocrine and ERK (MAP kinase) signaling pathways specifically through 5-HT1A receptor mechanisms in vivo (Q45228126)

11 December 2017

Tandospirone activates neuroendocrine and ERK (MAP kinase) signaling pathways specifically through 5-HT1A receptor mechanisms in vivo (English)

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11 December 2017

Nicole R Sullivan

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11 December 2017

James W Crane

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11 December 2017

Katerina J Damjanoska

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11 December 2017

Gonzalo A Carrasco

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11 December 2017

Deborah N D'Souza

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11 December 2017

Francisca Garcia

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11 December 2017

Louis D Van de Kar

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11 December 2017

18 January 2005

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Naunyn-Schmiedeberg's Archives of Pharmacology

11 December 2017

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11 December 2017

371

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11 December 2017

1

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11 December 2017

18-26

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https://scigraph.springernature.com/pub.10.1007/s00210-004-1005-7

11 December 2017

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Analysis of tandospirone (SM-3997) interactions with neurotransmitter receptor binding sites

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Regulation of 5-HT1A receptor function in brain following agonist or antidepressant administration

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CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs.

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5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus.

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ERK activation by G-protein-coupled receptors in mouse brain is receptor identity-specific

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Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus: II. Effect of pertussis and cholera toxins.

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Clinical effectiveness of tandospirone citrate (5-HT1A agonist) on patients with progressive supranuclear palsy

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The new generation of serotonergic anxiolytics: possible clinical roles

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Are receptors promiscuous? Intrinsic efficacy as a transduction phenomenon

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Long-term fluoxetine, but not desipramine, inhibits the ACTH and oxytocin responses to the 5-HT1A agonist, 8-OH-DPAT, in male rats

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The use and development of anxiolytics in Japan

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Isapirone is a partial agonist at 5-hydroxytryptamine 1A (5-HT1A) receptors in the rat hippocampus: electrophysiological evidence.

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[Effects of tandospirone citrate on frozen gait in patients with early stage of progressive supranuclear palsy, investigated by walk-induced activation single photon emission computed tomography method]

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Functional subsets of serotonergic neurones: implications for control of the hypothalamic-pituitary-adrenal axis

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12 December 2020

Hypothalamic paraventricular, but not supraoptic neurons, mediate the serotonergic stimulation of oxytocin secretion

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12 December 2020

Kinetics, brain uptake, and receptor binding of tandospirone and its metabolite 1-(2-pyrimidinyl)-piperazine

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12 December 2020

5-Hydroxytryptamine1A receptor/Gibetagamma stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of src in chinese hamster ovary fibroblasts

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12 December 2020

Ras-dependent activation of fibroblast mitogen-activated protein kinase by 5-HT1A receptor via a G protein beta gamma-subunit-initiated pathway.

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Synaptic interaction of serotonergic axons and corticotropin releasing factor (CRF) synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. A light and electron microscopic immunocytochemical study.

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Stimulation of 5-HT1A and 5-HT2/5-HT1C receptors induce oxytocin release in the male rat.

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Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine--I. Effects of acute and long-term administration of tandospirone on serotonin neurotransmission.

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Antidepressant-like activity of 5-HT1A agonists measured with the forced swim test

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The effect of buspirone on prolactin and growth hormone secretion in man

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Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences.

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Activation of a mitogen-activated protein kinase (ERK2) by the 5-hydroxytryptamine1A receptor is sensitive not only to inhibitors of phosphatidylinositol 3-kinase, but to an inhibitor of phosphatidylcholine hydrolysis

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12 December 2020

Tandospirone potentiates the fluoxetine-induced increases in extracellular dopamine via 5-HT(1A) receptors in the rat medial frontal cortex

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12 December 2020

Autoradiographic quantification of serotonin1A receptors in rat brain following antidepressant drug treatment

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12 December 2020

WAY-100635, a potent and selective 5-hydroxytryptamine1A antagonist, increases serotonergic neuronal activity in behaving cats: comparison with (S)-WAY-100135

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12 December 2020

In vivo drug action of tandospirone at 5-HT1A receptor examined using positron emission tomography and neuroendocrine response

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12 December 2020

The functional anatomy, neurochemistry, and pharmacology of anxiety.

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12 December 2020

Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: a comparative study with dorsal raphe neurons

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12 December 2020

5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain

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12 December 2020

Pharmacokinetic and pharmacodynamic studies of (R)-8-hydroxy-2-(di-n-propylamino)tetralin in the rat.

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12 December 2020

Development of 5-HT1A receptor antagonists

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12 December 2020

Tandospirone stimulates prolactin secretion in the rat by an action at serotonin-1A receptors.

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12 December 2020

Effect of buspirone on rat plasma prolactin levels and striatal dopamine turnover

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12 December 2020

A desensitization of hypothalamic 5-HT1A receptors by repeated injections of paroxetine: reduction in the levels of G(i) and G(o) proteins and neuroendocrine responses, but not in the density of 5-HT1A receptors.

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A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

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12 December 2020

A G protein couples serotonin and GABAB receptors to the same channels in hippocampus.

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12 December 2020

Whole-cell recordings of inwardly rectifying K+ currents activated by 5-HT1A receptors on dorsal raphe neurones of the adult rat

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12 December 2020

Electrophysiological evidence for a functional differentiation between subtypes of the 5-HT1 receptor

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12 December 2020

Desensitization of 5-HT1A receptors by 5-HT2A receptors in neuroendocrine neurons in vivo.

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Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine—II. Effects of acute administration of 1-PP and long-term adminstration of tandospirone on noradrenergic neurotransmission

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12 December 2020

The psychobiology of anxiolytic drug. Part 2: Pharmacological treatments of anxiety

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12 December 2020

Pharmacological properties of SM-3997: a new anxioselective anxiolytic candidate.

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12 December 2020

Serotonin and the neuroendocrine regulation of the hypothalamic--pituitary-adrenal axis in health and disease

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12 December 2020

Neuroendocrine pharmacology of stress.

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12 December 2020

WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors

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12 December 2020

Comparative localization of serotonin1A, 1C, and2 receptor subtype mRNAs in rat brain

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12 December 2020

Amelioration of frozen gait by tandospirone, a serotonin 1A agonist, in a patient with pure akinesia developing resistance to L-threo-3,4-dihydroxyphenylserine

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12 December 2020

Receptor reserve for 5-hydroxytryptamine1A-mediated inhibition of serotonin synthesis: possible relationship to anxiolytic properties of 5-hydroxytryptamine1A agonists.

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12 December 2020

Evidence that G(z)-proteins couple to hypothalamic 5-HT(1A) receptors in vivo.

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5HT drugs in animal models of anxiety

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Selective interaction of novel anxiolytics with 5-hydroxytryptamine1A receptors.

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Serotonin-1A anxiolytics: an overview

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5-HT inhibits lateral entorhinal cortical neurons of the rat in vitro by activation of potassium channel-coupled 5-HT1A receptors.

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12 December 2020

10.1007/S00210-004-1005-7

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11 December 2017

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