Translating materials design to the clinic (Q45214606)

10 December 2017

Translating materials design to the clinic (English)

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10 December 2017

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10 December 2017

Robert Langer

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PubMed ID

24150414

10 December 2017

language of work or name

English

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publication date

1 November 2013

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10 December 2017

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10 December 2017

12

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11

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10 December 2017

963-966

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https://scigraph.springernature.com/pub.10.1038/nmat3788

10 December 2017

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cites work

Chemistry. Nanomaterials for drug delivery

1 reference

Strategies in the design of nanoparticles for therapeutic applications

21 January 2018

1 reference

Bio-inspired, bioengineered and biomimetic drug delivery carriers

21 January 2018

1 reference

Nanoparticle therapeutics: an emerging treatment modality for cancer

21 January 2018

1 reference

Nanoparticle delivery of cancer drugs.

21 January 2018

1 reference

Scaling rules for diffusive drug delivery in tumor and normal tissues

21 January 2018

1 reference

Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology

21 January 2018

1 reference

NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

21 January 2018

1 reference

A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation

21 January 2018

1 reference

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size.

21 January 2018

1 reference

Tumor-targeted chemotherapy with the nanopolymer-based drug NC-6004 for oral squamous cell carcinoma

21 January 2018

1 reference

Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats

21 January 2018

1 reference

A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours.

21 January 2018

1 reference

Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting.

21 January 2018

1 reference

Biodegradable long-circulating polymeric nanospheres

21 January 2018

1 reference

Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile.

21 January 2018

1 reference

Nanoparticles that communicate in vivo to amplify tumour targeting

21 January 2018

1 reference

Docetaxel conjugate nanoparticles that target α-smooth muscle actin-expressing stromal cells suppress breast cancer metastasis.

21 January 2018

1 reference

The promises and pitfalls of RNA-interference-based therapeutics

21 January 2018

1 reference

Interfering with disease: a progress report on siRNA-based therapeutics

21 January 2018

1 reference

The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

21 January 2018

1 reference

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

1 reference

Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging

21 January 2018

1 reference

Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth.

21 January 2018

1 reference

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 January 2018

1 reference

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

21 January 2018

1 reference

Lipid-like materials for low-dose, in vivo gene silencing

21 January 2018

1 reference

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

21 January 2018

1 reference

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

21 January 2018

1 reference

Quantitative imaging of endosome acidification and single retrovirus fusion with distinct pools of early endosomes

21 January 2018

1 reference

Development of a novel endosomolytic diblock copolymer for siRNA delivery

21 January 2018

1 reference

Poly(N-isopropylacrylamide-co-propylacrylic acid) copolymers that respond sharply to temperature and pH.

21 January 2018

1 reference

Neutral polymeric micelles for RNA delivery

21 January 2018

1 reference

Diblock copolymers with tunable pH transitions for gene delivery

21 January 2018

1 reference

Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation

21 January 2018

1 reference

Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection

21 January 2018

1 reference

Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia.

21 January 2018

1 reference

Fusions of elastin-like polypeptides to pharmaceutical proteins.

21 January 2018

1 reference

Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance

21 January 2018

1 reference

A new era for cancer treatment: gold-nanoparticle-mediated thermal therapies

21 January 2018

1 reference

Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles

21 January 2018

1 reference

Near-infrared-resonant gold/gold sulfide nanoparticles as a photothermal cancer therapeutic agent

21 January 2018

1 reference

Immunonanoshells for targeted photothermal ablation in medulloblastoma and glioma: an in vitro evaluation using human cell lines

21 January 2018

1 reference

Antibody-conjugated gold-gold sulfide nanoparticles as multifunctional agents for imaging and therapy of breast cancer.

21 January 2018

1 reference

Vascular-targeted photothermal therapy of an orthotopic murine glioma model.

21 January 2018

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First-in-human testing of a wirelessly controlled drug delivery microchip.

21 January 2018

1 reference

Nanowired three-dimensional cardiac patches

21 January 2018

1 reference

Macroporous nanowire nanoelectronic scaffolds for synthetic tissues

21 January 2018

1 reference

Combinatorial discovery of polymers resistant to bacterial attachment

21 January 2018

1 reference

Vascular catheters with a nonleaching poly-sulfobetaine surface modification reduce thrombus formation and microbial attachment

21 January 2018

1 reference

Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice

21 January 2018

1 reference

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

21 January 2018

1 reference

Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination

21 January 2018

1 reference

Exploiting lymphatic transport and complement activation in nanoparticle vaccines

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24150414

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase II study of NK105, a paclitaxel-incorporating micellar nanoparticle, for previously treated advanced or recurrent gastric cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24150414

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NMAT3788

1 reference

PubMed ID

24150414

Dimensions Publication ID

10 December 2017

0 references

1 reference

PubMed ID

24150414