Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease. (Q45213390)

10 December 2017

Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease (English)

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12 May 2020

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1

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12 May 2020

Colin J. Barnstable

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12 May 2020

author name string

Balazs Horvath

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12 May 2020

John Elsworth

4

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Lichuan Yang

5

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M Flynt Beal

6

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Robert H Roth

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Russell T Matthews

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Tamas L Horvath

9

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language of work or name

English

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publication date

1 January 2005

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10 December 2017

Journal of Neuroscience

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volume

25

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issue

1

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page(s)

184-191

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UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells

12 May 2020

cites work

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12 December 2020

Mitochondrial events in the life and death of animal cells: a brief overview

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12 December 2020

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

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12 December 2020

Mitochondrial control of cell death

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12 December 2020

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

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12 December 2020

Coenzyme Q is an obligatory cofactor for uncoupling protein function

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12 December 2020

Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

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12 December 2020

Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

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12 December 2020

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

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12 December 2020

Coenzyme Q blocks biochemical but not receptor-mediated apoptosis by increasing mitochondrial antioxidant protection

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12 December 2020

Superoxide activates mitochondrial uncoupling proteins

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12 December 2020

Generation of reactive oxygen species by the mitochondrial electron transport chain

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12 December 2020

Possible physiological roles of mitochondrial uncoupling proteins--UCPn

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12 December 2020

Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury.

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12 December 2020

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

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12 December 2020

Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice

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12 December 2020

Mitochondrial uncoupling protein-2 protects the immature brain from excitotoxic neuronal death.

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12 December 2020

Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease

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12 December 2020

Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

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12 December 2020

Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state.

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12 December 2020

Uncoupling protein 2 prevents neuronal death including that occurring during seizures: a mechanism for preconditioning.

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12 December 2020

Parkinson's disease: mechanisms and models

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12 December 2020

Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice.

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12 December 2020

Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase

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12 December 2020

Nitrotyrosine as a marker for peroxynitrite-induced neurotoxicity: the beginning or the end of the end of dopamine neurons?

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12 December 2020

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

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12 December 2020

Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement

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12 December 2020

Molecular approach to thermogenesis in brown adipose tissue: cDNA cloning of the mitochondrial uncoupling protein

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12 December 2020

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

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12 December 2020

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

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12 December 2020

Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice.

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12 December 2020

BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast

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12 December 2020

10.1523/JNEUROSCI.4269-04.2005

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725213&resulttype=core&format=json

12 May 2020

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12 May 2020

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