16 Inhibition of mammalian protein methyltransferases by 5'-methylthioadenosine (MTA): A mechanism of action of dietary same? (Q45163529)

10 December 2017

title

16 Inhibition of mammalian protein methyltransferases by 5'-methylthioadenosine (MTA): A mechanism of action of dietary same? (English)

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10 December 2017

Steven G Clarke

1

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10 December 2017

publication date

1 January 2006

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10 December 2017

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10 December 2017

volume

24

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10 December 2017

page(s)

467-493

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Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine

10 December 2017

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Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription

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FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation

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The N-terminal SH4 region of the Src family kinase Fyn is modified by methylation and heterogeneous fatty acylation: role in membrane targeting, cell adhesion, and spreading

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Uptake and utilization of 5'-methylthioadenosine by cultured baby-hamster kidney cells

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Transport and metabolism of 5'-methylthioadenosine in human erythrocytes

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7 January 2021

Metabolism to methionine and growth stimulation by 5'-methylthioadenosine and 5'-methylthioinosine in mammalian cells

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7 January 2021

Dynamic chromatin boundaries delineate a latency control region of Epstein-Barr virus

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7 January 2021

Studies on substrate specificity of S-adenosylmethionine: protein-carboxyl methyltransferase from calf brain

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Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus. Unusual methyl-accepting affinity for D-aspartyl and N-succinyl-containing peptides

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The predominant protein-arginine methyltransferase from Saccharomyces cerevisiae

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7 January 2021

Inactivation of S-adenosylhomocysteine hydrolase by 5'-deoxy-5'-methylthioadenosine

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7 January 2021

Adenosine metabolism: modification by S-adenosylhomocysteine and 5'-methylthioadenosine

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7 January 2021

S-Adenosyl-L-methionine-dependent macromolecule methyltransferases: potential targets for the design of chemotherapeutic agents

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7 January 2021

Cascade of distinct histone modifications during collagenase gene activation

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7 January 2021

Induction of apoptosis in leukemia U937 cells by 5'-deoxy-5'-methylthioadenosine, a potent inhibitor of protein carboxylmethyltransferase.

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7 January 2021

S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies.

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7 January 2021

S-adenosyl-methionine in depression: A comprehensive review of the literature

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7 January 2021

S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies

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7 January 2021

Role of S-adenosyl-L-methionine in the treatment of liver diseases

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7 January 2021

S-Adenosylmethionine and methylation

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7 January 2021

Pharmacologic aspects of S-adenosylmethionine. Pharmacokinetics and pharmacodynamics

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7 January 2021

Bioavailability and lack of toxicity of S-adenosyl-L-methionine (SAMe) in humans

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7 January 2021

Cerebrospinal fluid S-adenosylmethionine (SAMe) and glutathione concentrations in HIV infection Effect of parenteral treatment with SAMe

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7 January 2021

Neuropharmacology of S-adenosyl-L-methionine

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7 January 2021

Metabolism of exogenous S-adenosylmethionine in isolated rat hepatocyte suspensions: methylation of plasma-membrane phospholipids without intracellular uptake

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7 January 2021

Uptake of S-adenosyl-L-methionine by rabbit erythrocytes

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7 January 2021

Uptake and metabolism of S-adenosyl-L-methionine by isolated rat hepatocytes

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S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytes

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7 January 2021

Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distribution

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7 January 2021

Transport of S-adenosylmethionine in isolated rat liver mitochondria

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7 January 2021

Identification and functional reconstitution of yeast mitochondrial carrier for S-adenosylmethionine.

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7 January 2021

Transport of sulfonium compounds. Characterization of the s-adenosylmethionine and s-methylmethionine permeases from the yeast Saccharomyces cerevisiae

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7 January 2021

Antioxidant properties of S-adenosyl-L-methionine in Fe(2+)-initiated oxidations

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7 January 2021

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7 January 2021

Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine

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7 January 2021

Arginine methylation an emerging regulator of protein function

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7 January 2021

2 The family of protein arginine metkyltransferases.

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7 January 2021

3 Diverse roles of protein arginine methyltransferases

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7 January 2021

4 Structure of protein arginine methyltransferases

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7 January 2021

5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

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7 January 2021

Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine

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7 January 2021

Lipopolysaccharide-induced NF-kappa B activation in mouse 70Z/3 pre-B lymphocytes is inhibited by mevinolin and 5'-methylthioadenosine: roles of protein isoprenylation and carboxyl methylation reactions

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7 January 2021

Inhibition of cytokine production and endothelial expression of adhesion antigens by 5'-methylthioadenosine

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7 January 2021

S-adenosylmethionine (SAMe) modulates interleukin-10 and interleukin-6, but not TNF, production via the adenosine (A2) receptor

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7 January 2021

Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase

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7 January 2021

A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor

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7 January 2021

Are STATS arginine-methylated?

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7 January 2021

Arginine methylation regulates IL-2 gene expression: a role for protein arginine methyltransferase 5 (PRMT5).

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7 January 2021

Inhibition by 5'-methylthioadenosine of cell growth and tyrosine kinase activity stimulated by fibroblast growth factor receptor in human gliomas

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7 January 2021

Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution

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7 January 2021

Direct evidence for methylation of arginine residues in high molecular weight forms of basic fibroblast growth factor

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7 January 2021

Biochemical analysis of the arginine methylation of high molecular weight fibroblast growth factor-2.

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7 January 2021

Regulation of astrocyte GFAP expression by TGF-beta1 and FGF-2.

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7 January 2021

Differential inhibition of nerve growth factor and epidermal growth factor effects on the PC12 pheochromocytoma line

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7 January 2021

Early responses of PC-12 cells to NGF and EGF: effect of K252a and 5'-methylthioadenosine on gene expression and membrane protein methylation.

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7 January 2021

Nerve growth factor induces a succession of increases in isoprenylated methylated small GTP-binding proteins of PC-12 pheochromocytoma cells

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7 January 2021

Selective inhibition of nerve growth factor-stimulated protein kinases by K-252a and 5'-S-methyladenosine in PC12 cells

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7 January 2021

Nerve growth factor-specific regulation of protein methylation during neuronal differentiation of PC12 cells.

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7 January 2021

Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1

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7 January 2021

PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family

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7 January 2021

Inhibition of lymphocyte transformation by a naturally occurring metabolite: 5'-methylthioadenosine

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7 January 2021

Effects of inhibitors of spermidine and spermine synthesis on polyamine concentrations and growth of transformed mouse fibroblasts

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7 January 2021

Mechanism of action of 5'-methylthioadenosine in S49 cells

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7 January 2021

Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.

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7 January 2021

Translating the Histone Code

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7 January 2021

10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins

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7 January 2021

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

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7 January 2021

S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S).

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7 January 2021

13 Protein L-isoaspartyl, D-aspartyl O-methyltransferases: Catalysts for protein repair.

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7 January 2021

Effect of 5'-methylthioadenosine on in vivo methyl esterification of human erythrocyte membrane proteins

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7 January 2021

Inhibition of the synthesis of polyamines and macromolecules by 5'-methylthioadenosine and 5'-alkylthiotubercidins in BHK21 cells

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7 January 2021

Protein kinase A signaling: "cross-talk" with other pathways in endocrine cells

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7 January 2021

5'-Deoxy-5'-methylthioadenosine: a nucleoside which differentiates between adenosine receptor types

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7 January 2021

Modulation of agonist responses at the A(1) adenosine receptor by an irreversible antagonist, receptor-G protein uncoupling and by the G protein activation state

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7 January 2021

Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors

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7 January 2021

S-adenosyl-L-homocysteine and 5'-methylthioadenosine inhibit binding of [3H]flunitrazepam to rat brain membranes

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7 January 2021

5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.

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7 January 2021

Modulation of diphthamide synthesis by 5'-deoxy-5'-methylthioadenosine in murine lymphoma cells

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7 January 2021

5'-Methylthioadenosine in urine from normal subjects and cancer patients

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7 January 2021

S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]

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7 January 2021

Small molecule regulators of protein arginine methyltransferases

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7 January 2021

10.1016/S1874-6047(06)80018-1

Identifiers

DOI

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10 December 2017

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