Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants (Q45161041)

10 December 2017

Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants (English)

1 reference

10 December 2017

Rituparna Chakrabarti

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ruth Geiss-Friedlander

11

1 reference

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2 June 2020

Ellen Reisinger

15

1 reference

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2 June 2020

12

Henning Urlaub

1 reference

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2 June 2020

13

Nils Brose

1 reference

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2 June 2020

author name string

Nicola Strenzke

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Hanan Al-Moyed

3

1 reference

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2 June 2020

Alexandra Müller

4

1 reference

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2 June 2020

Gerhard Hoch

5

1 reference

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2 June 2020

Tina Pangrsic

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Gulnara Yamanbaeva

7

1 reference

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2 June 2020

Christof Lenz

8

1 reference

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2 June 2020

Kuan-Ting Pan

9

1 reference

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2 June 2020

Elisabeth Auge

10

1 reference

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2 June 2020

Carolin Wichmann

14

1 reference

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2 June 2020

language of work or name

English

0 references

publication date

11 October 2016

1 reference

10 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

35

1 reference

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2 June 2020

issue

23

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2 June 2020

page(s)

2519-2535

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describes a project that uses

2 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5283603/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Molecular determinants of the human α2C-adrenergic receptor temperature-sensitive intracellular traffic

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Uniquantal release through a dynamic fusion pore is a candidate mechanism of hair cell exocytosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A new probe for super-resolution imaging of membranes elucidates trafficking pathways

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Evidence for genotype-phenotype correlation for OTOF mutations

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Frequency tuning in the behaving mouse: different bandwidths for discrimination and generalization

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Loudness adaptation accompanying ribbon synapse and auditory nerve disorders

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Otoferlin: a multi-C2 domain protein essential for hearing

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Spike encoding of neurotransmitter release timing by spiral ganglion neurons of the cochlea.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Sharp Ca²⁺ nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Modulation of α(2C) adrenergic receptor temperature-sensitive trafficking by HSP90

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Screening mutations of OTOF gene in Chinese patients with auditory neuropathy, including a familial case of temperature-sensitive auditory neuropathy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Temperature-sensitive auditory neuropathy associated with an otoferlin mutation: Deafening fever!

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Behaviorally measured audiograms and gap detection thresholds in CBA/CaJ mice

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

OTOF mutations revealed by genetic analysis of hearing loss families including a potential temperature sensitive auditory neuropathy allele

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

The afferent synapse of cochlear hair cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Non-syndromic recessive auditory neuropathy is the result of mutations in the otoferlin (OTOF) gene

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Transmitter release at the hair cell ribbon synapse

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Kinetics of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse of the mouse

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Transient deafness due to temperature-sensitive auditory neuropathy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Spike activity recorded from the organ of Corti

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

A prevalent founder mutation and genotype-phenotype correlations of OTOF in Japanese patients with auditory neuropathy

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Novel OTOF mutations in Brazilian patients with auditory neuropathy.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Probing the mechanism of exocytosis at the hair cell ribbon synapse.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Temperature enhances exocytosis efficiency at the mouse inner hair cell ribbon synapse.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Gap detection deficits in rats with tinnitus: a potential novel screening tool.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Hair cell synaptic ribbons are essential for synchronous auditory signalling.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283603

Mutations in the OTOF gene in Taiwanese patients with auditory neuropathy

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27729456

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Calcium Dependence of Exocytosis and Endocytosis at the Cochlear Inner Hair Cell Afferent Synapse

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27729456

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.15252/EMBJ.201694564

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27729456%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference