HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage. (Q45138498)

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22 February 2020

title

HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage (English)

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22 February 2020

5

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6

Dong-young Noh

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22 February 2020

author name string

Ji-hyun Ju

1

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22 February 2020

Wonseok Yang

2

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22 February 2020

Sunhwa Oh

3

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22 February 2020

KeeSoo Nam

4

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22 February 2020

Incheol Shin

7

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22 February 2020

language of work or name

English

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publication date

1 April 2013

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22 February 2020

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22 February 2020

volume

451

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22 February 2020

page(s)

123-134

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22 February 2020

issue

1

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A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

22 February 2020

cites work

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Control of apoptosis and mitotic spindle checkpoint by survivin

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Prognostic importance of survivin in breast cancer

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Biologic and therapeutic role of HER2 in cancer

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Trastuzumab--mechanism of action and use in clinical practice

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Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis

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Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells

21 January 2018

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Expression of HER-2 in MCF-7 breast cancer cells modulates anti-apoptotic proteins Survivin and Bcl-2 via the extracellular signal-related kinase (ERK) and phosphoinositide-3 kinase (PI3K) signalling pathways

21 January 2018

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Notch signaling: cell fate control and signal integration in development

21 January 2018

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Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane

21 January 2018

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Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

21 January 2018

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Notch-1 signaling facilitates survivin expression in human non-small cell lung cancer cells

21 January 2018

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Expression of active Akt protects against tamoxifen-induced apoptosis in MCF-7 Cells

21 January 2018

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Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility

21 January 2018

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Akt isoform-specific inhibition of MDA-MB-231 cell proliferation

21 January 2018

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Down-regulation of Notch-dependent transcription by Akt in vitro

21 January 2018

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PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

21 January 2018

1 reference

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Mitogen-activated protein kinase kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation.

21 January 2018

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Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7

21 January 2018

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Identification of a novel activation domain in the Notch-responsive transcription factor CSL

21 January 2018

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The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

21 January 2018

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Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei

21 January 2018

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Assembly of the presenilin γ-/ε-secretase complex.

21 January 2018

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X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

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Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

21 January 2018

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Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex

21 January 2018

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Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.

21 January 2018

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Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

21 January 2018

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XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer

21 January 2018

1 reference

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Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

21 January 2018

1 reference

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

1 reference

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Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization

21 January 2018

1 reference

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A single amino acid change (Asp 53 --> Ala53) converts Survivin from anti-apoptotic to pro-apoptotic

21 January 2018

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A survivin double point mutant has potent inhibitory effect on the growth of hepatocellular cancer cells

21 January 2018

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Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

21 January 2018

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Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

21 January 2018

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EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.

21 January 2018

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EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer

21 January 2018

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Regulation of Notch1 gene expression by p53 in epithelial cells

21 January 2018

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p21 Inhibits Thr161Phosphorylation of Cdc2 to Enforce the G2DNA Damage Checkpoint

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20121716

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23323858%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference