CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation (Q45107882)

9 December 2017

CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation (English)

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9 December 2017

Neil C Henderson

1

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9 December 2017

Elizabeth A Collis

2

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9 December 2017

Alison C Mackinnon

3

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9 December 2017

Kenneth J Simpson

4

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9 December 2017

Christopher Haslett

5

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9 December 2017

Roy Zent

6

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9 December 2017

Mark Ginsberg

7

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9 December 2017

Tariq Sethi

8

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9 December 2017

language of work or name

English

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publication date

12 October 2004

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Journal of Biological Chemistry

9 December 2017

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9 December 2017

279

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9 December 2017

54731-54741

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9 December 2017

52

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Analysis of the expression of the 4F2 surface antigen in normal and neoplastic fibroblastic human cells of embryonic and adult origin.

9 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Structure, expression and regulation of the murine 4F2 heavy chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Identification of a new epitope of the 4F2/44D7 molecular complex present on sarcolemma and isolated cardiac fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Isolation and characterization of a heterodimeric surface antigen on human melanoma cells and evidence that it is the 4F2 cell activation/proliferation molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Malignant transformation of NIH3T3 cells by overexpression of early lymphocyte activation antigen CD98.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Diversity of gene expression in adenocarcinoma of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Integrins, oncogenes, and anchorage independence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Complementation of dominant suppression implicates CD98 in integrin activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

CD98-mediated links between amino acid transport and beta 1 integrin distribution in polarized columnar epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Cross-linking CD98 promotes integrin-like signaling and anchorage-independent growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

CD98 induces LFA-1-mediated cell adhesion in lymphoid cells via activation of Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Pro-adhesive and chemotactic activities of thrombospondin-1 for breast carcinoma cells are mediated by alpha3beta1 integrin and regulated by insulin-like growth factor-1 and CD98

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Beta1 integrins show specific association with CD98 protein in low density membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Transformation of BALB3T3 cells caused by over-expression of rat CD98 heavy chain (HC) requires its association with light chain: mis-sense mutation in a cysteine residue of CD98HC eliminates its transforming activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Modulation of beta1A integrin functions by tyrosine residues in the beta1 cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

The cytoplasmic tyrosines of integrin subunit beta1 are involved in focal adhesion kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

24 Evaluation of chemical carcinogenicity by in vitro neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

21 January 2018

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Distinct domains of CD98hc regulate integrins and amino acid transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Focal adhesion kinase as a potential target in oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Functional heterodimeric amino acid transporters lacking cysteine residues involved in disulfide bond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408700200

21 January 2018

Identifiers

DOI

10.1074/JBC.M408700200

1 reference

9 December 2017

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