Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin (Q45096277)

9 December 2017

Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin (English)

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9 December 2017

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8

Jan H M Schellens

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9 December 2017

Robert C A M van Waardenburg

1

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9 December 2017

Laurina A de Jong

2

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9 December 2017

Maria A J van Eijndhoven

3

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9 December 2017

Caroline Verseyden

4

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9 December 2017

Dick Pluim

5

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9 December 2017

Lars E T Jansen

6

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9 December 2017

Mary-Ann Bjornsti

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9 December 2017

language of work or name

English

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publication date

6 October 2004

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Journal of Biological Chemistry

9 December 2017

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9 December 2017

279

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52

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54502-54509

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Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases

9 December 2017

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https://api.crossref.org/works/10.1074%2FJBC.M410103200

DNA topoisomerases: structure, function, and mechanism

21 January 2018

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Cellular roles of dna topoisomerases: a molecular perspective

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Repair of and checkpoint response to topoisomerase I-mediated DNA damage

21 January 2018

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Tumor cell death induced by topoisomerase-targeting drugs.

21 January 2018

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Mechanisms of resistance to topoisomerase I-targeting drugs

21 January 2018

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Clinical use of topoisomerase I inhibitors in anticancer treatment

21 January 2018

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Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro

21 January 2018

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Sequences of topotecan and cisplatin: phase I, pharmacologic, and in vitro studies to examine sequence dependence

21 January 2018

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Topotecan preceded by oxaliplatin using a 3 week schedule: a phase I study in advanced cancer patients

21 January 2018

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Tyrosine kinase inhibitor STI-571: the new wonder drug of cancer therapy

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Induction of topoisomerase I cleavage complexes by 1-beta -D-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells

21 January 2018

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Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex

21 January 2018

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Stabilization of eukaryotic topoisomerase II-DNA cleavage complexes

21 January 2018

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Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions

21 January 2018

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Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

21 January 2018

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Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

21 January 2018

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Platinum-based anticancer agents: innovative design strategies and biological perspectives.

21 January 2018

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New clues for platinum antitumor chemistry: kinetically controlled metal binding to DNA.

21 January 2018

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A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons

21 January 2018

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Basis for effective combination cancer chemotherapy with antimetabolites

21 January 2018

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32P-postlabeling assay for the quantification of the major platinum-DNA adducts

21 January 2018

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Active site mutations in DNA topoisomerase I distinguish the cytotoxic activities of camptothecin and the indolocarbazole, rebeccamycin

21 January 2018

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Effects of CPT-11 in combination with other anti-cancer agents in culture

21 January 2018

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Cytotoxic effects of topotecan combined with various anticancer agents in human cancer cell lines

21 January 2018

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The solution structure of a DNA duplex containing the cis-Pt(NH3)2[d(-GTG-)-N7(G),N7(G)] adduct, as determined with high-field NMR and molecular mechanics/dynamics

21 January 2018

1 reference

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Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

21 January 2018

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NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin

21 January 2018

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Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

21 January 2018

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Oxaliplatin, tetraplatin, cisplatin, and carboplatin: spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M410103200

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9 December 2017

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