ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells (Q45022808)

8 December 2017

ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells (English)

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8 December 2017

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8 December 2017

Sassan Hafizi

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author name string

Xuemin Wang

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2

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PubMed ID

15317677

8 December 2017

Adrian H Chester

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3

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PubMed ID

15317677

8 December 2017

Magdi H Yacoub

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4

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8 December 2017

1 September 2004

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American Journal of Physiology Heart and Circulatory Physiology

8 December 2017

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8 December 2017

287

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8 December 2017

3

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8 December 2017

H1232-8

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S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment

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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

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A target for phosphoinositide 3-kinase: Akt/PKB.

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Control of p70 s6 kinase by kinase activity of FRAP in vivo

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Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

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Culture of renal arteriolar smooth muscle cells. Mitogenic responses to angiotensin II

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Effect of high dose angiotensin-converting enzyme inhibition on restenosis: final results of the MARCATOR Study, a multicenter, double-blind, placebo-controlled trial of cilazapril. The Multicenter American Research Trial With Cilazapril After Angio

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Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells

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Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells.

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Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs

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Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

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The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins

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Rheb fills a GAP between TSC and TOR.

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The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin

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Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast.

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Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase

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Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells.

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Drosophila Rheb GTPase is required for cell cycle progression and cell growth

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An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

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p70 S6 kinase: an enigma with variations

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Molecular mechanisms for the control of translation by insulin

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Immunological characterization of avian MAP kinases: evidence for nuclear localization

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Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, randomised controlled trial (E-SIRIUS).

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Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators

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Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

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Akt/protein kinase B promotes organ growth in transgenic mice

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Rapamycin attenuates load-induced cardiac hypertrophy in mice

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Rheb is an essential regulator of S6K in controlling cell growth in Drosophila

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4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

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Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes

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Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes

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Amino acid availability regulates p70 S6 kinase and multiple translation factors

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Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

21 January 2018

1 reference

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Ventricular-specific expression of angiotensin II type 2 receptors causes dilated cardiomyopathy and heart failure in transgenic mice.

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Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinase

21 January 2018

1 reference

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10.1152/AJPHEART.00040.2004

21 January 2018

Identifiers

DOI

1 reference

8 December 2017

1 reference

PubMed ID

15317677