Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation (Q44989715)

8 December 2017

Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation (English)

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8 December 2017

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8 December 2017

Manning T Schmidt

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8 December 2017

Michael D Jackson

series ordinal

3

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8 December 2017

John M Denu

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4

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8 December 2017

language of work or name

English

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publication date

21 July 2004

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Journal of Biological Chemistry

8 December 2017

8

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based on heuristic

inferred from page(s)

published in

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8 December 2017

279

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8 December 2017

40122-40129

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8 December 2017

38

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Enzymatic activities of Sir2 and chromatin silencing

8 December 2017

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

The molecular biology of the SIR proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

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Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

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A link between transcription and intermediary metabolism: a role for Sir2 in the control of acetyl-coenzyme A synthetase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Genetics and the specificity of the aging process

21 January 2018

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Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407484200

Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407484200

Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Human Sir2 and the 'silencing' of p53 activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Calorie restriction extends yeast life span by lowering the level of NADH.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407484200

Mechanism of Nicotinamide Inhibition and Transglycosidation by Sir2 Histone/Protein Deacetylases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

The amide rotational barriers in picolinamide and nicotinamide: NMR and ab initio studies

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Sensing electrons: protein phosphatase redox regulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Biophysical chemistry of metabolic reaction sequences in concentrated enzyme solution and in the cell

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structure and Substrate Binding Properties of cobB, a Sir2 Homolog Protein Deacetylase from Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structural basis for the NAD-dependent deacetylase mechanism of Sir2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structure of a Sir2 enzyme bound to an acetylated p53 peptide

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Crystal structure of a SIR2 homolog-NAD complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structure and autoregulation of the yeast Hst2 homolog of Sir2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2′-O-Acetyl ADP Ribose and Histone Peptide

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structure of the histone deacetylase SIRT2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structural basis for the mechanism and regulation of Sir2 enzymes.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

The structure of NADH in the enzyme dTDP-d-glucose dehydratase (RmlB)

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M407484200

21 January 2018

Identifiers

DOI

10.1074/JBC.M407484200

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8 December 2017

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