Galphaq/11 signaling induces apoptosis through two pathways involving reduction of Akt phosphorylation and activation of RhoA in HeLa cells (Q44970208)

7 December 2017

Galphaq/11 signaling induces apoptosis through two pathways involving reduction of Akt phosphorylation and activation of RhoA in HeLa cells (English)

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7 December 2017

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Hiroshi Ueda

1

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7 December 2017

Rika Morishita

2

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7 December 2017

Shuh Narumiya

3

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7 December 2017

Kanefusa Kato

4

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7 December 2017

Tomiko Asano

5

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7 December 2017

language of work or name

English

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publication date

1 August 2004

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Experimental Cell Research

7 December 2017

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7 December 2017

298

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7 December 2017

1

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7 December 2017

207-217

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The importance of G-protein beta lambda subunits

7 December 2017

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G protein beta gamma subunits.

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Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

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Cardiomyocyte apoptosis induced by Galphaq signaling is mediated by permeability transition pore formation and activation of the mitochondrial death pathway.

7 January 2021

1 reference

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Constitutively active Galphaq and Galpha13 trigger apoptosis through different pathways

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Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling

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Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy

7 January 2021

1 reference

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Galpha11 induces caspase-mediated proteolytic activation of Rho-associated kinase, ROCK-I, in HeLa cells

7 January 2021

1 reference

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

7 January 2021

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Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

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Angiotensin II activates programmed myocyte cell death in vitro

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

7 January 2021

1 reference

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G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

7 January 2021

1 reference

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Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

7 January 2021

1 reference

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Dual regulation of Akt/protein kinase B by heterotrimeric G protein subunits

7 January 2021

1 reference

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Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation.

7 January 2021

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

7 January 2021

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Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

7 January 2021

1 reference

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Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation

7 January 2021

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The biochemistry of apoptosis

7 January 2021

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Bax kappa, a novel Bax splice variant from ischemic rat brain lacking an ART domain, promotes neuronal cell death

7 January 2021

1 reference

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

7 January 2021

1 reference

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The PI3K-PDK1 connection: more than just a road to PKB

7 January 2021

1 reference

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Primary structure of a gamma subunit of G protein, gamma 12, and its phosphorylation by protein kinase C

7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Insulin signalling and the regulation of glucose and lipid metabolism

1 reference

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Receptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of Kv1.2 channel activity

7 January 2021

1 reference

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Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.

7 January 2021

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Potent activation of RhoA by Galpha q and Gq-coupled receptors.

7 January 2021

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RGS2/G0S8 is a selective inhibitor of Gqalpha function

7 January 2021

1 reference

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Serum response factor activation by muscarinic receptors via RhoA. Novel pathway specific to M1 subtype involving calmodulin, calcineurin, and Pyk2.

7 January 2021

1 reference

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G protein betagamma subunits induce stress fiber formation and focal adhesion assembly in a Rho-dependent manner in HeLa cells

7 January 2021

1 reference

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Regulation of Rac and Cdc42 pathways by G(i) during lysophosphatidic acid-induced cell spreading

7 January 2021

1 reference

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Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity

7 January 2021

2 references

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7 January 2021

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.015

inferred from DOI database lookup

7 January 2021

based on heuristic

ADP-ribosylation factor 6 regulates actin cytoskeleton remodeling in coordination with Rac1 and RhoA.

1 reference

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G(alpha)11 signaling through ARF6 regulates F-actin mobilization and GLUT4 glucose transporter translocation to the plasma membrane

7 January 2021

1 reference

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Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.

7 January 2021

1 reference

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RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

7 January 2021

1 reference

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Geranylgeranylated RhoB is sufficient to mediate tissue-specific suppression of Akt kinase activity by farnesyltransferase inhibitors

7 January 2021

1 reference

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RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development

7 January 2021

1 reference

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10.1016/J.YEXCR.2004.04.015

7 January 2021

Identifiers

DOI

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release_gaobxoa6sffvrgtldjwxk7cha4

7 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gaobxoa6sffvrgtldjwxk7cha4

mapped directly with Wikidata item

24 November 2022

based on heuristic

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