Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2. (Q44923699)

7 December 2017

Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2. (English)

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7 December 2017

Masakazu Hirouchi

1

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7 December 2017

Hiroshi Suzuki

2

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7 December 2017

Masaya Itoda

3

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7 December 2017

Shogo Ozawa

4

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7 December 2017

Jun-ichi Sawada

5

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7 December 2017

Ichiro Ieiri

6

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7 December 2017

Kenji Ohtsubo

7

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7 December 2017

Yuichi Sugiyama

8

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7 December 2017

1 May 2004

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7 December 2017

Pharmaceutical Research

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7 December 2017

21

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7 December 2017

5

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7 December 2017

742-748

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Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2.

7 December 2017

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12 December 2020

Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats.

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12 December 2020

Hepatic secretion of conjugated drugs and endogenous substances

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12 December 2020

Mechanism of glutathione S-conjugate transport in canalicular and basolateral rat liver plasma membranes

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12 December 2020

Clinical relevance of genetic polymorphisms in the human CYP2C subfamily

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12 December 2020

Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome

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12 December 2020

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis

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12 December 2020

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

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12 December 2020

Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects

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12 December 2020

The drug efflux pump MRP2: regulation of expression in physiopathological situations and by endogenous and exogenous compounds

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12 December 2020

Genetic defects in hepatobiliary transport.

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12 December 2020

Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28.

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12 December 2020

Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome

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12 December 2020

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

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12 December 2020

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

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12 December 2020

A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors

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12 December 2020

Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome

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12 December 2020

Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

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12 December 2020

The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans

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12 December 2020

Mammalian ABC transporters in health and disease

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12 December 2020

Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells.

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12 December 2020

Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method

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12 December 2020

Interindividual variability in inhibition and induction of cytochrome P450 enzymes

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12 December 2020

Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition

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12 December 2020

Involvement of an organic anion transporter (canalicular multispecific organic anion transporter/multidrug resistance-associated protein 2) in gastrointestinal secretion of glutathione conjugates in rats

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12 December 2020

Transporters for bile acids and organic anions.

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12 December 2020

Cytochromes P450 and metabolism of xenobiotics

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12 December 2020

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

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12 December 2020

A splice mutation in the human canalicular multispecific organic anion transporter gene causes Dubin-Johnson syndrome

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12 December 2020

Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).

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12 December 2020

10.1023/B:PHAM.0000026422.06207.33

Identifiers

DOI

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7 December 2017

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