The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide (Q44913883)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

7 December 2017

retracted paper

2 references

Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide (English)

1 reference

Europe PubMed Central

7 December 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

7

object named as

Paul Dent

1 reference

Europe PubMed Central

7 December 2017

6

object named as

Sarah Spiegel

1 reference

Europe PubMed Central

7 December 2017

author name string

Roberto R Rosato

1

1 reference

Europe PubMed Central

7 December 2017

Sonia C Maggio

2

1 reference

Europe PubMed Central

7 December 2017

Jorge A Almenara

3

1 reference

Europe PubMed Central

7 December 2017

Shawn G Payne

4

1 reference

Europe PubMed Central

7 December 2017

Peter Atadja

5

1 reference

Europe PubMed Central

7 December 2017

Steven Grant

8

1 reference

Europe PubMed Central

7 December 2017

publication date

27 September 2005

1 reference

Europe PubMed Central

7 December 2017

Molecular Pharmacology

1 reference

Europe PubMed Central

7 December 2017

69

1 reference

Europe PubMed Central

7 December 2017

1

1 reference

Europe PubMed Central

7 December 2017

216-225

1 reference

Europe PubMed Central

7 December 2017

Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Selective growth inhibition of tumor cells by a novel histone deacetylase inhibitor, NVP-LAQ824.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Cellular Events Involved in Butyric Acid-Induced T Cell Apoptosis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Control of mitochondrial integrity by Bcl-2 family members and caspase-independent cell death.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Histone deacetylase inhibitors in clinical development

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Evidence of a functional role for the cyclin-dependent kinase-inhibitor p21WAF1/CIP1/MDA6 in promoting differentiation and preventing mitochondrial dysfunction and apoptosis induced by sodium butyrate in human myelomonocytic leukemia cells (U937).

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Ceramide in apoptosis: an overview and current perspectives

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Ceramide and cell death receptor clustering

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Histone acetylation/deacetylation and cancer: an "open" and "shut" case?

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Cotreatment with histone deacetylase inhibitor LAQ824 enhances Apo-2L/tumor necrosis factor-related apoptosis inducing ligand-induced death inducing signaling complex activity and apoptosis of human acute leukemia cells

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Synergistic induction of mitochondrial damage and apoptosis in human leukemia cells by flavopiridol and the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA).

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Involvement of the acid sphingomyelinase pathway in uva-induced apoptosis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.105.017145

Identifiers

10.1124/MOL.105.017145

1 reference

Europe PubMed Central

7 December 2017

1 reference

Europe PubMed Central

7 December 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44913883&oldid=2056786489"