Lateral hypothalamic signaling mechanisms underlying feeding stimulation: differential contributions of Src family tyrosine kinases to feeding triggered either by NMDA injection or by food deprivation. (Q44820500)

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scientific article published in November 2004

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English	Lateral hypothalamic signaling mechanisms underlying feeding stimulation: differential contributions of Src family tyrosine kinases to feeding triggered either by NMDA injection or by food deprivation.	scientific article published in November 2004

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5 January 2020

Lateral hypothalamic signaling mechanisms underlying feeding stimulation: differential contributions of Src family tyrosine kinases to feeding triggered either by NMDA injection or by food deprivation (English)

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5 January 2020

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5 January 2020

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Herman H Cheung

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Elizabeth R Gillard

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Jennifer A Palarca

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Derek S Welsbie

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James W Gurd

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B Glenn Stanley

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1 November 2004

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Journal of Neuroscience

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5 January 2020

10603-10615

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5 January 2020

Lateral hypothalamic NMDA receptor subunits NR2A and/or NR2B mediate eating: immunochemical/behavioral evidence

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https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

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The tyrosine kinase inhibitor genistein directly inhibits GABAA receptors.

1 reference

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12 December 2020

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

1 reference

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12 December 2020

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On the mechanism of genistein-induced activation of protein kinase A-dependent Cl- conductance in cardiac myocytes

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A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling

1 reference

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Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

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Structural basis for selective inhibition of Src family kinases by PP1

1 reference

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FAK+ and PYK2/CAKbeta, two related tyrosine kinases highly expressed in the central nervous system: similarities and differences in the expression pattern

1 reference

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Kinases of the Src family: structure and functions

1 reference

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12 December 2020

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Altered association of protein tyrosine kinases with postsynaptic densities after transient cerebral ischemia in the rat brain

1 reference

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12 December 2020

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Interactions of cyclic nucleotide-gated channel subunits and protein tyrosine kinase probed with genistein.

1 reference

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12 December 2020

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The postsynaptic density protein PSD-95 differentially regulates insulin- and Src-mediated current modulation of mouse NMDA receptors expressed in Xenopus oocytes.

1 reference

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12 December 2020

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Modulation of hypothalamic NMDA receptor function by cyclic AMP-dependent protein kinase and phosphatases.

1 reference

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12 December 2020

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Biological properties of genistein. A review of in vitro and in vivo data

1 reference

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12 December 2020

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Direct inhibition of glycine receptors by genistein, a tyrosine kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

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Protein tyrosine kinase structure and function

1 reference

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12 December 2020

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Src tyrosine kinase is a novel direct effector of G proteins.

1 reference

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12 December 2020

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Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor

1 reference

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12 December 2020

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N-methyl-D-aspartate receptor subunit NR2B is widely expressed throughout the rat diencephalon: an immunohistochemical study

1 reference

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12 December 2020

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Selected glimpses into the activation and function of Src kinase

1 reference

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12 December 2020

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Src inhibitors: drugs for the treatment of osteoporosis, cancer or both?

1 reference

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12 December 2020

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CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus

1 reference

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12 December 2020

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Co-operative effect of c-Src tyrosine kinase and Stat3 in activation of hepatocyte growth factor expression in mammary carcinoma cells

1 reference

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12 December 2020

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Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation

1 reference

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12 December 2020

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G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation

1 reference

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12 December 2020

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Molecular determinants for Csk-catalyzed tyrosine phosphorylation of the Src tail

1 reference

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12 December 2020

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Pharmacotherapy of obesity: targets and perspectives

1 reference

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12 December 2020

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Differential expression of orexin receptors 1 and 2 in the rat brain.

1 reference

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12 December 2020

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NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity

1 reference

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12 December 2020

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Soy isoflavone supplements antagonize reproductive behavior and estrogen receptor alpha- and beta-dependent gene expression in the brain

1 reference

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12 December 2020

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Immunohistochemical characterization of localization of long-form leptin receptor (OB-Rb) in neurochemically defined cells in the ovine hypothalamus

1 reference

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12 December 2020

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Reverse microdialysis of N-methyl-D-aspartic acid into the lateral hypothalamus of rats: effects on feeding and other behaviors

1 reference

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12 December 2020

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Regional differences in feeding and other behaviors elicited by N-methyl-D-aspartic acid in the rodent hypothalamus: a reverse microdialysis mapping study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

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PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

1 reference

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12 December 2020

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DMSO as a vehicle for central injections: tests with feeding elicited by norepinephrine injected into the paraventricular nucleus

1 reference

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12 December 2020

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Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: focus on orexin targets involved in control of food and water intake

1 reference

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12 December 2020

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Cross signaling, cell specificity, and physiology

1 reference

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12 December 2020

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Augmentation of drug reward by chronic food restriction: behavioral evidence and underlying mechanisms.

1 reference

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12 December 2020

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Multiple neural systems controlling food intake and body weight

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

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The need to feed: homeostatic and hedonic control of eating

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

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Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

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Extracellular glutamate increases in the lateral hypothalamus during meal initiation and GABA peaks during satiation: Microdialysis measurement every 30 s

1 reference

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12 December 2020

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Production of knockout rats using ENU mutagenesis and a yeast-based screening assay

1 reference

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12 December 2020

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Targeting mammalian genes--rats join in and mice move ahead

1 reference

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12 December 2020

based on heuristic

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Lateral hypothalamic neuropeptides in reward and drug addiction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noncanonical signaling by ionotropic kainate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

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Comparative distribution of neuropeptide Y Y1 and Y5 receptors in the rat brain by using immunohistochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for neuropeptide Y mediation of eating produced by food deprivation and for a variant of the Y1 receptor mediating this peptide's effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

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Tyrphostins: tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin-induced signal transduction pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src kinases: a hub for NMDA receptor regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genistein inhibits protein histidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use and specificity of genistein as inhibitor of protein-tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical localization of the neuron-specific form of the c-src gene product, pp60c-src(+), in rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyr527 is phosphorylated in pp60c-src: implications for regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-specific src oncogene mRNA mapped in rat brain by in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

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The lateral hypothalamus: a primary site mediating excitatory amino acid-elicited eating

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of NMDA receptors by tyrosine kinases and phosphatases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential tyrosine phosphorylation of N-methyl-D-aspartate receptor subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lateral hypothalamic injections of glutamate, kainic acid, D,L-alpha-amino-3-hydroxy-5-methyl-isoxazole propionic acid or N-methyl-D-aspartic acid rapidly elicit intense transient eating in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

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Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

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Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The perifornical area: the major focus of (a) patchily distributed hypothalamic neuropeptide Y-sensitive feeding system(s).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genistein is a natural inhibitor of hexose and dehydroascorbic acid transport through the glucose transporter, GLUT1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein tyrosine kinase-mediated potentiation of currents from cloned NMDA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feeding, drug abuse, and the sensitization of reward by metabolic need.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA channel regulation by channel-associated protein tyrosine kinase Src.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subtype-specific regulation of recombinant NMDA receptor-channels by protein tyrosine kinases of the src family

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct block of voltage-sensitive sodium channels by genistein, a tyrosine kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropeptide Y treatment and food deprivation increase cyclic AMP response element-binding in rat hypothalamus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of eating by the second messenger cAMP in the perifornical and lateral hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA receptor coagonist glycine site: evidence for a role in lateral hypothalamic stimulation of feeding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient ischemia differentially increases tyrosine phosphorylation of NMDA receptor subunits 2A and 2B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphotyrosine signaling and the single cell:metazoan boundary

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular glutamate increases in the lateral hypothalamus and decreases in the nucleus accumbens during feeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structures of Src-family tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

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Cellular functions regulated by Src family kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

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Does tyrosine kinase modulate delayed-rectifier K channels in guinea pig ventricular cells?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The second messenger cAMP elicits eating by an anatomically specific action in the perifornical hypothalamus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distributions of leptin receptor mRNA isoforms in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and characterization of splice variants of PYK2, a focal adhesion kinase-related protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eating induced by perifornical cAMP is behaviorally selective and involves protein kinase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A peptide activator of endogenous tyrosine kinase enhances synaptic currents mediated by NMDA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of calcineurin by the tyrphostin class of tyrosine kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noncatalytic inhibition of cyclic nucleotide-gated channels by tyrosine kinase induced by genistein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genistein inhibits slow component delayed-rectifier K currents via a tyrosine kinase-independent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15564576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3390-04.2004

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5 January 2020

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Europe PubMed Central

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5 January 2020

1 reference

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5 January 2020

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