Replication-dependent 65R-->K reversion in human immunodeficiency virus type 1 reverse transcriptase double mutant K65R + L74V. (Q44819964)

6 December 2017

Replication-dependent 65R-->K reversion in human immunodeficiency virus type 1 reverse transcriptase double mutant K65R + L74V. (English)

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6 December 2017

6

Raymond F Schinazi

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6 December 2017

2

Viktoria Nurpeisov

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6 December 2017

Prem L Sharma

1

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6 December 2017

Kimberly Lee

series ordinal

3

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6 December 2017

Sara Skaggs

series ordinal

4

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6 December 2017

Christina Amat Di San Filippo

series ordinal

5

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6 December 2017

language of work or name

English

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publication date

1 April 2004

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6 December 2017

13

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inferred from page(s)

published in

Virology

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6 December 2017

321

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6 December 2017

2

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6 December 2017

222-234

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Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

6 December 2017

2 references

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The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase

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Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

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1 reference

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In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3'-azido-3'-deoxythymidine

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1 reference

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1 reference

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1 reference

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In vitro selection and molecular characterization of human immunodeficiency virus type 1 with reduced sensitivity to 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).

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Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line.

7 January 2021

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Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine

7 January 2021

1 reference

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K65R mutation of human immunodeficiency virus type 1 reverse transcriptase encodes cross-resistance to 9-(2-phosphonylmethoxyethyl)adenine

7 January 2021

1 reference

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Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs

7 January 2021

1 reference

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Mechanism of action and in vitro activity of 1',3'-dioxolanylpurine nucleoside analogues against sensitive and drug-resistant human immunodeficiency virus type 1 variants

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Evidence for late stage compartmentalization of HIV-1 resistance mutations between lymph node and peripheral blood mononuclear cells.

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Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. CNA2001 Investigative Group

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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Improvement of interleukin 2 production, clonogenic capability and restoration of stromal cell function in human immunodeficiency virus-type-1 patients after highly active antiretroviral therapy.

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Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes.

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Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails

7 January 2021

1 reference

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HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy.

7 January 2021

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Reversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine.

7 January 2021

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Fluorescent dye terminator sequencing methods for quantitative determination of replication fitness of human immunodeficiency virus type 1 containing the codon 74 and 184 mutations in reverse transcriptase

7 January 2021

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Despite high concordance, distinct mutational and phenotypic drug resistance profiles in human immunodeficiency virus type 1 RNA are observed in gastrointestinal mucosal biopsy specimens and peripheral blood mononuclear cells compared with plasma

7 January 2021

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Mechanism-based suppression of dideoxynucleotide resistance by K65R human immunodeficiency virus reverse transcriptase using an alpha-boranophosphate nucleoside analogue.

7 January 2021

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7 January 2021

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Impact of simian immunodeficiency virus (SIV) infection on lymphocyte numbers and T-cell turnover in different organs of rhesus monkeys

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Molecular evidence for drug-induced compartmentalization of HIV-1 quasispecies in a patient with periodic changes to HAART.

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Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity

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The prevalence and determinants of the K65R mutation in HIV-1 reverse transcriptase in tenofovir-naive patients

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Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase

7 January 2021

1 reference

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Second-site reversion of a human immunodeficiency virus type 1 reverse transcriptase mutant that restores enzyme function and replication capacity.

7 January 2021

1 reference

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7 January 2021

Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val.

1 reference

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Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years

1 reference

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7 January 2021

10.1016/J.VIROL.2003.11.013

Identifiers

DOI

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release_5k26m35txjdffc6bboh7kmwi5a

6 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5k26m35txjdffc6bboh7kmwi5a

24 November 2022

mapped directly with Wikidata item

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