Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38. (Q44729061)

5 December 2017

Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38. (English)

1 reference

5 December 2017

0 references

Laurent Lamalice

1

1 reference

5 December 2017

François Houle

series ordinal

2

1 reference

5 December 2017

Guillaume Jourdan

series ordinal

3

1 reference

5 December 2017

Jacques Huot

series ordinal

4

1 reference

5 December 2017

language of work or name

English

0 references

publication date

1 January 2004

1 reference

5 December 2017

1 reference

5 December 2017

23

1 reference

5 December 2017

434-445

1 reference

5 December 2017

2

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207034

5 December 2017

0 references

cites work

SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

Adhesion in cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

Geldanamycin specifically modulates thrombin-mediated morphological changes in mouse neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

Thrombin receptor signaling to cytoskeleton requires Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

Signaling via vascular endothelial growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

The stress-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

A model for co-expression pattern analysis of genes implicated in angiogenesis and tumour cell invasion in cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Regulation of VEGF-induced endothelial cell PAF synthesis: role of p42/44 MAPK, p38 MAPK and PI3K pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Relative effects of VEGF-A and VEGF-C on endothelial cell proliferation, migration and PAF synthesis: Role of neuropilin-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

p21-activated kinase 1 participates in tracheal smooth muscle cell migration by signaling to p38 Mapk

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Characterization of 45-kDa/54-kDa HSP27 kinase, a stress-sensitive kinase which may activate the phosphorylation-dependent protective function of mammalian 27-kDa heat-shock protein HSP27.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

The role of fibroblast growth factors in vascular development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

[Regulation of the endothelial function and angiogenesis by vascular endothelial growth factor-A (VEGF-A]

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Integrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Pathological significance of vascular endothelial growth factor A isoform expression in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Sck is expressed in endothelial cells and participates in vascular endothelial growth factor-induced signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Cdc42/Rac1-mediated activation primes PAK2 for superactivation by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Rho GTPases. Integrating integrin signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Erratum: Stress fibres take shape

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Integrating the VEGF signals leading to actin-based motility in vascular endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Flt-1-mediated down-regulation of endothelial cell proliferation through pertussis toxin-sensitive G proteins, beta gamma subunits, small GTPase CDC42, and partly by Rac-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207034

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207034

1 reference

Dimensions Publication ID

5 December 2017

0 references

1 reference