Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase. (Q44724575)

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17 November 2019

title

Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase (English)

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17 November 2019

3

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17 November 2019

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Vincent G H Eijsink

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17 November 2019

author name string

Bjørnar Synstad

1

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17 November 2019

Sigrid Gåseidnes

2

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17 November 2019

Gert Vriend

4

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17 November 2019

Jens E Nielsen

5

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17 November 2019

language of work or name

English

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publication date

1 January 2004

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17 November 2019

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17 November 2019

volume

271

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17 November 2019

page(s)

253-262

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17 November 2019

issue

2

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Structural and sequence-based classification of glycoside hydrolases

17 November 2019

cites work

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Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins

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The 1.8 A resolution structure of hevamine, a plant chitinase/lysozyme, and analysis of the conserved sequence and structure motifs of glycosyl hydrolase family 18

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The third chitinase gene (chiC) of Serratia marcescens 2170 and the relationship of its product to other bacterial chitinases

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Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

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X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family

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NAG-thiazoline, An N -Acetyl-β-hexosaminidase Inhibitor That Implicates Acetamido Participation

21 January 2018

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Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes

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21 January 2018

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Structural insights into the catalytic mechanism of a family 18 exo-chitinase

21 January 2018

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High resolution structural analyses of mutant chitinase A complexes with substrates provide new insight into the mechanism of catalysis

21 January 2018

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Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase

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Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state

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Site-directed mutagenesis and functional analysis of active site acidic amino acid residues D142, D144 and E146 in Manduca sexta (tobacco hornworm) chitinase

21 January 2018

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On the evaluation and optimization of protein X-ray structures for pKa calculations

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WHAT IF: a molecular modeling and drug design program

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21 January 2018

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