Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6. (Q44666534)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14634128%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6 (English)

1 reference

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G protein-coupled receptor

21 December 2019

main subject

0 references

1 reference

5

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21 December 2019

7

Robert J Lefkowitz

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21 December 2019

author name string

Annemieke Kavelaars

1

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21 December 2019

Anne Vroon

2

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21 December 2019

Roel P Raatgever

3

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21 December 2019

Alan M Fong

4

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21 December 2019

Dhavalkumar D Patel

6

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21 December 2019

Cobi J Heijnen

8

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21 December 2019

language of work or name

English

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publication date

1 December 2003

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21 December 2019

published in

Journal of Immunology

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21 December 2019

volume

171

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21 December 2019

issue

11

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21 December 2019

page(s)

6128-6134

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Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors

21 December 2019

cites work

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Signalling through the leukotriene B4 receptor involves both alphai and alpha16, but not alphaq or alpha11 G-protein subunits

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Oxidative stress decreases G protein-coupled receptor kinase 2 in lymphocytes via a calpain-dependent mechanism

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Changes in the G-protein-coupled receptor desensitization machinery during relapsing-progressive experimental allergic encephalomyelitis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Phosphorylation of the N-formyl peptide receptor is required for receptor internalization but not chemotaxis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

The importance of leukotrienes in airway inflammation in a mouse model of asthma

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11 October 2022

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Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 that regulate signaling and receptor internalization

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11 October 2022

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Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

1 reference

11 October 2022

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Molecular and biological characterization of the murine leukotriene B4 receptor expressed on eosinophils

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

G protein-coupled receptor kinases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Altered inflammatory responses in leukotriene-deficient mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Adjuvant arthritis induces down-regulation of G protein-coupled receptor kinases in the immune system.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Dissociation of chemotaxis from agonist-induced receptor internalization in a lymphocyte cell line transfected with CCR2B. Evidence that directed migration does not require rapid modulation of signaling at the receptor level

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

T lymphocytes and neutrophil granulocytes differ in regulatory signaling and migratory dynamics with regard to spontaneous locomotion and chemotaxis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Requirement of phosphatidylinositol 3-kinase activation and calcium influx for leukotriene B4-induced enzyme release

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.171.11.6128

Identifiers

DOI

10.4049/JIMMUNOL.171.11.6128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14634128%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference