Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3. (Q44661736)

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9 January 2020

title

Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3 (English)

1 reference

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9 January 2020

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4

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9 January 2020

author name string

Göran Dahl

series ordinal

1

1 reference

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9 January 2020

Anja Sandström

series ordinal

2

1 reference

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9 January 2020

Eva Akerblom

series ordinal

3

1 reference

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9 January 2020

language of work or name

English

0 references

publication date

19 October 2007

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9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17949436%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

274

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9 January 2020

issue

22

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9 January 2020

page(s)

5979-5986

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Challenges and successes in developing new therapies for hepatitis C.

9 January 2020

cites work

1 reference

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Serine protease of hepatitis C virus expressed in insect cells as the NS3/4A complex.

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The nonstructural protein 3 protease/helicase requires an intact protease domain to unwind duplex RNA efficiently

21 January 2018

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Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV RNA-dependent RNA polymerase

21 January 2018

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Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

21 January 2018

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

21 January 2018

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Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain

21 January 2018

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Expression and purification of recombinant full-length NS3 protease-helicase from a new variant of Hepatitis C virus

21 January 2018

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Tetrapeptides as potent protease inhibitors of Hepatitis C Virus full-length NS3 (protease-helicase/NTPase).

21 January 2018

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Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-Length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals

21 January 2018

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Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3.

21 January 2018

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Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors

21 January 2018

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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

21 January 2018

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Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C.

21 January 2018

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Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease

21 January 2018

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Potent peptide inhibitors of human hepatitis C virus NS3 protease are obtained by optimizing the cleavage products

21 January 2018

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Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

21 January 2018

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On the size of the active site in proteases. I. Papain

21 January 2018

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