Substrate discrimination by formamidopyrimidine-DNA glycosylase: a mutational analysis (Q44649058)

5 December 2017

Substrate discrimination by formamidopyrimidine-DNA glycosylase: a mutational analysis (English)

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5 December 2017

4

Suse Broyde

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5 December 2017

Elena I Zaika

1

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5 December 2017

Rebecca A Perlow

2

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5 December 2017

Eileen Matz

3

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5 December 2017

Rotem Gilboa

5

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5 December 2017

Arthur P Grollman

6

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5 December 2017

Dmitry O Zharkov

7

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5 December 2017

language of work or name

English

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publication date

7 November 2003

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Journal of Biological Chemistry

5 December 2017

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5 December 2017

279

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5 December 2017

4849-4861

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5 December 2017

6

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Imidazole open ring 7-methylguanine : An inhibitor of DNA synthesis

5 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Ring-opened 7-methylguanine residues in DNA are a block to in vitro DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Effects of a guanine-derived formamidopyrimidine lesion on DNA replication: translesion DNA synthesis, nucleotide insertion, and extension kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Fapy.dG instructs Klenow exo(-) to misincorporate deoxyadenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Mutagenesis by 8-oxoguanine: an enemy within

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

A repair system for 8-oxo-7,8-dihydrodeoxyguanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

The enigma of endonuclease VIII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA

21 January 2018

1 reference

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Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions

21 January 2018

1 reference

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The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death

21 January 2018

1 reference

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Mechanism of DNA strand nicking at apurinic/apyrimidinic sites by Escherichia coli [formamidopyrimidine]DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

3'- and 5'-strand cleavage reactions catalyzed by the Fpg protein from Escherichia coli occur via successive beta- and delta-elimination mechanisms, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Characterization of a cross-linked DNA-endonuclease VIII repair complex by electrospray ionization mass spectrometry

21 January 2018

1 reference

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Studies on the catalytic mechanism of five DNA glycosylases. Probing for enzyme-DNA imino intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

The catalytic mechanism of Fpg protein. Evidence for a Schiff base intermediate and amino terminus localization of the catalytic site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Combining structural and bioinformatics methods for the analysis of functionally important residues in DNA glycosylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Amino acid-base interactions: a three-dimensional analysis of protein-DNA interactions at an atomic level

21 January 2018

1 reference

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Amino-aromatic interactions in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Thermodynamic, kinetic, and structural basis for recognition and repair of 8-oxoguanine in DNA by Fpg protein from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

An oxidative damage-specific endonuclease from rat liver mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Excision of oxidatively damaged DNA bases by the human alpha-hOgg1 protein and the polymorphic alpha-hOgg1(Ser326Cys) protein which is frequently found in human populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Kinetics of excision of purine lesions from DNA by Escherichia coli Fpg protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Substrate specificity and excision kinetics of Escherichia coli endonuclease VIII (Nei) for modified bases in DNA damaged by free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Diffusion-driven mechanisms of protein translocation on nucleic acids. 1. Models and theory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Diffusion-driven mechanisms of protein translocation on nucleic acids. 3. The Escherichia coli lac repressor--operator interaction: kinetic measurements and conclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Biological consequences of free radical-damaged DNA bases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

DNA lesion recognition by the bacterial repair enzyme MutM

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Base excision repair: NMR backbone assignments of Escherichia coli formamidopyrimidine-DNA glycosylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Stopped-flow kinetic studies of the interaction between Escherichia coli Fpg protein and DNA substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Influence of the oxidatively damaged adduct 8-oxodeoxyguanosine on the conformation, energetics, and thermodynamic stability of a DNA duplex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Role of active site residues in the glycosylase step of T4 endonuclease V. Computer simulation studies on ionization states

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Uracil-DNA glycosylase acts by substrate autocatalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Role of base flipping in specific recognition of damaged DNA by repair enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Role of DNA flexibility in sequence-dependent activity of uracil DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Novel activity of Escherichia coli mismatch uracil-DNA glycosylase (Mug) excising 8-(hydroxymethyl)-3,N4-ethenocytosine, a potential product resulting from glycidaldehyde reaction

21 January 2018

1 reference

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Structural insights by molecular dynamics simulations into differential repair efficiency for ethano-A versus etheno-A adducts by the human alkylpurine-DNA N-glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Powering DNA repair through substrate electrostatic interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Role of lysine-57 in the catalytic activities of Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg protein).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Determination of active site residues in Escherichia coli endonuclease VIII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Purine bases, nucleosides, and nucleotides: aqueous solution redox chemistry and transformation reactions of their radical cations and e- and OH adducts

21 January 2018

1 reference

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Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Structural and conformational analyses of 8-hydroxy-2'-deoxyguanosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).dA(anti) alignment at lesion site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Characterization ofEscherichia coliEndonuclease VIII

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

NH2-terminal proline acts as a nucleophile in the glycosylase/AP-lyase reaction catalyzed by Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg) protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Synthesis of 2'-deoxy-7,8-dihydro-8-oxoguanosine and 2'-deoxy-7,8-dihydro-8-oxoadenosine and their incorporation into oligomeric DNA

21 January 2018

1 reference

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A modified version of the Cornell et al. force field with improved sugar pucker phases and helical repeat

21 January 2018

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Conformational analysis of the major DNA adduct derived from the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline

21 January 2018

1 reference

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Protein sequence alignments: a strategy for the hierarchical analysis of residue conservation.

21 January 2018

1 reference

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Involvement of phylogenetically conserved acidic amino acid residues in catalysis by an oxidative DNA damage enzyme formamidopyrimidine glycosylase

21 January 2018

1 reference

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Enzymatic Processing of Uracil Glycol, a Major Oxidative Product of DNA Cytosine

21 January 2018

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Repair and coding properties of 5-hydroxy-5-methylhydantoin nucleosides inserted into DNA oligomers

21 January 2018

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Characterization of a novel 8-oxoguanine-DNA glycosylase activity in Escherichia coli and identification of the enzyme as endonuclease VIII

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310262200

Diffusion-driven mechanisms of protein translocation on nucleic acids. 2. The Escherichia coli lac repressor-operator interaction: equilibrium measurements

21 January 2018

1 reference

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MutY DNA glycosylase: base release and intermediate complex formation

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M310262200

1 reference

5 December 2017

1 reference