Nuclear localization of Vpr is crucial for the efficient replication of HIV-1 in primary CD4+ T cells (Q44645285)

5 December 2017

Nuclear localization of Vpr is crucial for the efficient replication of HIV-1 in primary CD4+ T cells (English)

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5 December 2017

Sayuki Iijima

1

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5 December 2017

Yuko Nitahara-Kasahara

2

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5 December 2017

Kiyonori Kimata

3

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5 December 2017

Wen Zhong Zhuang

4

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5 December 2017

Masakazu Kamata

5

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5 December 2017

Maya Isogai

6

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5 December 2017

Masanao Miwa

7

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5 December 2017

Yasuko Tsunetsugu-Yokota

8

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5 December 2017

Yoko Aida

9

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5 December 2017

language of work or name

English

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publication date

1 October 2004

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5 December 2017

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5 December 2017

327

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5 December 2017

2

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5 December 2017

249-261

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Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

5 December 2017

2 references

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

The human immunodeficiency virus type 1 Vpr transactivator: cooperation with promoter-bound activator domains and binding to TFIIB

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Flavopiridol inhibits P-TEFb and blocks HIV-1 replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

HIV-1, Vpr and the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Two putative alpha-helical domains of human immunodeficiency virus type 1 Vpr mediate nuclear localization by at least two mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Growth ability of human immunodeficiency virus type 1 auxiliary gene mutants in primary blood macrophage cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Induction of cell differentiation by human immunodeficiency virus 1 vpr.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: effect on stability and virion incorporation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Role of the conserved dipeptide Gly75 and Cys76 on HIV-1 Vpr function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

HIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

NMR structure of the HIV-1 regulatory protein VPR

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Human immunodeficiency virus type 1 Vpr gene product prevents cell proliferation on mouse NIH3T3 cells without the G2 arrest of the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

A carboxy-terminally truncated form of the Vpr protein of human immunodeficiency virus type 1 retards cell proliferation independently of G(2) arrest of the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

A carboxy-terminally truncated form of the human immunodeficiency virus type 1 Vpr protein induces apoptosis via G(1) cell cycle arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Induction of apoptosis by the Vpr protein of human immunodeficiency virus type 1 occurs independently of G(2) arrest of the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Vpr protein of human immunodeficiency virus type 1 forms cation-selective channels in planar lipid bilayers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Viral protein R regulates nuclear import of the HIV-1 pre-integration complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Functional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Function and conformation of wild-type p53 protein are influenced by mutations in bovine leukemia virus-induced B-cell lymphosarcoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Yeast-derived human immunodeficiency virus type 1 p55(gag) virus-like particles activate dendritic cells (DCs) and induce perforin expression in Gag-specific CD8(+) T cells by cross-presentation of DCs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Interaction of virion protein Vpr of human immunodeficiency virus type 1 with cellular transcription factor Sp1 and trans-activation of viral long terminal repeat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Characterization of a leucine-zipper-like domain in Vpr protein of human immunodeficiency virus type 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Pleiotropic effects of HIV-1 protein R (Vpr) on morphogenesis and cell survival in fission yeast and antagonism by pentoxifylline.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Mutational analysis of the human immunodeficiency virus vpr open reading frame.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

The putative alpha helix 2 of human immunodeficiency virus type 1 Vpr contains a determinant which is responsible for the nuclear translocation of proviral DNA in growth-arrested cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

Vpr-induced cell cycle arrest is conserved among primate lentiviruses.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

Monocyte-derived cultured dendritic cells are susceptible to human immunodeficiency virus infection and transmit virus to resting T cells in the process of nominal antigen presentation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

Effect of human immunodeficiency virus type 1 protein R (vpr) gene expression on basic cellular function of fission yeast Schizosaccharomyces pombe.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.06.024

7 January 2021

10.1016/J.VIROL.2004.06.024

Identifiers

DOI

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5 December 2017

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