In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease (Q44626420)

4 December 2017

In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease (English)

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4 December 2017

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Byoung Boo Seo

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4 December 2017

Eiko Nakamaru-Ogiso

2

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4 December 2017

Terence R Flotte

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4 December 2017

Akemi Matsuno-Yagi

4

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4 December 2017

Takao Yagi

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4 December 2017

language of work or name

English

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publication date

16 March 2006

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Journal of Biological Chemistry

4 December 2017

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4 December 2017

281

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4 December 2017

20

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4 December 2017

14250-14255

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Analysis of the subunit composition of complex I from bovine heart mitochondria

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Organization of iron-sulfur clusters in respiratory complex I.

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Human complex I defects in neurodegenerative diseases

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Complex I and Parkinson's disease

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Rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria: the enzyme expressed in Escherichia coli acts as a member of the respiratory chain in the host cells.

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1 reference

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Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells

21 January 2018

1 reference

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Modulation of oxidative phosphorylation of human kidney 293 cells by transfection with the internal rotenone-insensitive NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae

21 January 2018

1 reference

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Use of the NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae as a possible cure for complex I defects in human cells

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1 reference

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Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene

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1 reference

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A single-subunit NADH-quinone oxidoreductase renders resistance to mammalian nerve cells against complex I inhibition

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Isolation and inactivation of the nuclear gene encoding the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae

21 January 2018

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Primary structure and import pathway of the rotenone-insensitive NADH-ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae

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Parkinson's disease: mechanisms and models

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Molecular pathophysiology of Parkinson's disease

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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Functional expression of the single subunit NADH dehydrogenase in mitochondria in vivo: a potential therapy for complex I deficiencies

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The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice.

21 January 2018

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Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospi

21 January 2018

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21 January 2018

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Etiology of Parkinson's disease: Genetics and environment revisited

21 January 2018

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D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease

21 January 2018

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Mitochondrial gene therapy: an arena for the biomedical use of inteins

21 January 2018

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Gene therapy of mitochondrial DNA mutations: a brief, biased history of allotopic expression in mammalian cells

21 January 2018

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Assembly of functional proton-translocating ATPase complex in yeast mitochondria with cytoplasmically synthesized subunit 8, a polypeptide normally encoded within the organelle

21 January 2018

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Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus

21 January 2018

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Rescue of a mitochondrial deficiency causing Leber Hereditary Optic Neuropathy

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Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats

21 January 2018

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Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes

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21 January 2018

Identifiers

DOI

10.1074/JBC.M600922200

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4 December 2017

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