Cytoplasmic c-Abl provides a molecular 'Rheostat' controlling carcinoma cell survival and invasion (Q44573123)

4 December 2017

Cytoplasmic c-Abl provides a molecular 'Rheostat' controlling carcinoma cell survival and invasion (English)

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4 December 2017

Kristin H Kain

1

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4 December 2017

Stacy Gooch

series ordinal

2

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4 December 2017

Richard L Klemke

series ordinal

3

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4 December 2017

language of work or name

English

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publication date

1 September 2003

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4 December 2017

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4 December 2017

22

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4 December 2017

38

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4 December 2017

6071-6080

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206930

4 December 2017

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Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

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Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

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Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo

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Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

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Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix

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Phosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesis

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Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase

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Phosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptor

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Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes

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CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

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Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport

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Integrins regulate the association and phosphorylation of paxillin by c-Abl

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Extranuclear apoptosis. The role of the cytoplasm in the execution phase

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Production of high-titer helper-free retroviruses by transient transfection

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The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene

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Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase

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Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells

21 January 2018

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Evidence for a conserved role for CRKII and Rac in engulfment of apoptotic cells

21 January 2018

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The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity

21 January 2018

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Inhibition of c-Abl tyrosine kinase activity by filamentous actin

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Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension

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Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

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Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

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7 January 2021

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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7 January 2021

Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

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7 January 2021

Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway

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7 January 2021

Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases

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7 January 2021

c-Abl kinase regulates the protein binding activity of c-Crk

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7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

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7 January 2021

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

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7 January 2021

Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis

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7 January 2021

Essential roles for the Abl and Arg tyrosine kinases in neurulation

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7 January 2021

Cell migration: a physically integrated molecular process

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7 January 2021

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

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7 January 2021

Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

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7 January 2021

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

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7 January 2021

Autoinhibition of c-Abl

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7 January 2021

Social controls on cell survival and cell death

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7 January 2021

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

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7 January 2021

Crk family adaptor proteins trans-activate c-Abl kinase

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7 January 2021

Apoptotic regulation by the Crk adapter protein mediated by interactions with Wee1 and Crm1/exportin

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7 January 2021

Abl: mechanisms of regulation and activation.

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7 January 2021

Mechanisms and genes of cellular suicide

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7 January 2021

Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species

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7 January 2021

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

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7 January 2021

Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.

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7 January 2021

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206930

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4 December 2017

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