Catalytic mechanism of the maloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26. (Q44571693)

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7 November 2019

title

Catalytic mechanism of the maloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26 (English)

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Sphingomonas paucimobilis

7 November 2019

main subject

object named as

Sphingomonas paucimobilis

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1

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7 November 2019

Radka Chaloupkova

3

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7 November 2019

Martin Klvana

4

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7 November 2019

author name string

Marta Monincová

2

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7 November 2019

Yuji Nagata

5

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7 November 2019

Dick B Janssen

6

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7 November 2019

Jiri Damborský

7

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7 November 2019

language of work or name

English

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publication date

1 September 2003

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Journal of Biological Chemistry

7 November 2019

published in

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7 November 2019

volume

278

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7 November 2019

page(s)

45094-45100

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7 November 2019

issue

46

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The alpha/beta hydrolase fold

7 November 2019

cites work

1 reference

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Comparative binding energy analysis of the substrate specificity of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10.

21 January 2018

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Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase

21 January 2018

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Histidine 289 is essential for hydrolysis of the alkyl-enzyme intermediate of haloalkane dehalogenase

21 January 2018

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Site-directed mutagenesis and oxygen isotope incorporation studies of the nucleophilic aspartate of haloalkane dehalogenase.

21 January 2018

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Kinetics of halide release of haloalkane dehalogenase: evidence for a slow conformational change.

21 January 2018

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Specificity and kinetics of haloalkane dehalogenase.

21 January 2018

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Analysis of the reaction mechanism and substrate specificity of haloalkane dehalogenases by sequential and structural comparisons

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The plasmid-located haloalkane dehalogenase gene from Rhodococcus rhodochrous NCIMB 13064.

21 January 2018

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Steady-state and pre-steady-state kinetic analysis of halopropane conversion by a rhodococcus haloalkane dehalogenase

21 January 2018

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WHAT IF: a molecular modeling and drug design program

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Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate range

21 January 2018

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Kinetic analysis and X-ray structure of haloalkane dehalogenase with a modified halide-binding site

21 January 2018

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Functionally relevant motions of haloalkane dehalogenases occur in the specificity-modulating cap domains

21 January 2018

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Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis

21 January 2018

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Haloalkane dehalogenases: steady-state kinetics and halide inhibition

21 January 2018

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Biochemical characterization of broad-specificity enzymes using multivariate experimental design and a colorimetric microplate assay: characterization of the haloalkane dehalogenase mutants.

21 January 2018

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Reconstruction of mycobacterial dehalogenase Rv2579 by cumulative mutagenesis of haloalkane dehalogenase LinB

21 January 2018

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Repositioning the catalytic triad aspartic acid of haloalkane dehalogenase: effects on stability, kinetics, and structure.

21 January 2018

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Generating segmental mutations in haloalkane dehalogenase: a novel part in the directed evolution toolbox

21 January 2018

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Biodegradation of 1,2,3-trichloropropane through directed evolution and heterologous expression of a haloalkane dehalogenase gene

21 January 2018

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Chlorine kinetic isotope effects on the haloalkane dehalogenase reaction.

21 January 2018

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Chlorine kinetic isotope effects on enzymatic dehalogenations

21 January 2018

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21 January 2018

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Influence of mutations of Val226 on the catalytic rate of haloalkane dehalogenase

21 January 2018

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Computer modelling of microbial hydrolytic dehalogenation

21 January 2018

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Purification and characterization of a bacterial dehalogenase with activity toward halogenated alkanes, alcohols and ethers

21 January 2018

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Construction and Characterization of Histidine-Tagged Haloalkane Dehalogenase (LinB) of a New Substrate Class from a γ-Hexachlorocyclohexane-Degrading Bacterium, Sphingomonas paucimobilis UT26

21 January 2018

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Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

21 January 2018

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Identification of the catalytic triad in the haloalkane dehalogenase from Sphingomonas paucimobilis UT26

21 January 2018

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Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M307056200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952988%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference