Phase I and pharmacodynamic study of Triapine, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia (Q44551806)

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object named as

Guillermo Garcia-Manero

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4 December 2017

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Jorge E Cortes

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4 December 2017

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William Plunkett

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4 December 2017

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Mario Sznol

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4 December 2017

1

Francis J Giles

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4 December 2017

5

Randy A Brown

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4 December 2017

17

John F DiPersio

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4 December 2017

Paula M Fracasso

2

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4 December 2017

Yesid Alvarado

7

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4 December 2017

Deborah A Thomas

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4 December 2017

Lisa P Wright

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4 December 2017

Tom Samson

12

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4 December 2017

Ann Cahill

13

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4 December 2017

Paula Lambert

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4 December 2017

Varsha Gandhi

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4 December 2017

1 December 2003

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4 December 2017

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1077-1083

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4 December 2017

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4 December 2017

Acute myeloid leukemia

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Ribonucleotide Reductase—a Radical Enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

From RNA to DNA, why so many ribonucleotide reductases?

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Evolving role of ribonucleoside reductase inhibitors in hematologic malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

The enzyme ribonucleotide reductase: target for antitumor and anti-HIV therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Dynamics of pyrimidine deoxynucleoside triphosphate pools in relationship to DNA synthesis in 3T6 mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

DNA precursor asymmetries, replication fidelity, and variable genome evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Drug action on ribonucleotide reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Ribonucleotide reductase as a chemotherapeutic target

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Syntheses and antitumor activities of potent inhibitors of ribonucleotide reductase: 3-amino-4-methylpyridine-2-carboxaldehyde-thiosemicarba-zone (3-AMP), 3-amino-pyridine-2-carboxaldehyde-thiosemicarbazone (3-AP) and its water-soluble prodrugs

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Synthesis and antitumor activity of amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Synthesis and biological activity of 3- and 5-amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Cellular pharmacodynamics and plasma pharmacokinetics of parenterally infused hydroxyurea during a phase I clinical trial in chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021

Deoxyribonucleoside triphosphate pools in human diploid fibroblasts and their modulation by hydroxyurea and deoxynucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900118-8

7 January 2021