Synthesis and in vitro evaluation of novel small molecule inhibitors of bacterial arylamine N-acetyltransferases (NATs). (Q44508038)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Synthesis and in vitro evaluation of novel small molecule inhibitors of bacterial arylamine N-acetyltransferases (NATs) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

6

Edith Sim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

Edward W Brooke

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Stephen G Davies

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Andrew W Mulvaney

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Minoru Okada

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Frédérique Pompeo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Isaac M Westwood

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

language of work or name

English

0 references

publication date

1 August 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

Bioorganic & Medicinal Chemistry Letters

5 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

2527-2530

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Eubacterial arylamine N-acetyltransferases - identification and comparison of 18 members of the protein family with conserved active site cysteine, histidine and aspartate residues

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Genetic control of isoniazid metabolism in man

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Partial purification and properties of the isoniazid transacetylase in human liver. Its relationship to the acetylation of p-aminosalicylic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Arylamine N-acetyltransferase of Mycobacterium tuberculosis is a polymorphic enzyme and a site of isoniazid metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Cloning and characterization of arylamine N-acetyltransferase genes from Mycobacterium smegmatis and Mycobacterium tuberculosis: increased expression results in isoniazid resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Evidence towards the role of arylamine N-acetyltransferase in Mycobacterium smegmatis and development of a specific antiserum against the homologous enzyme of Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Structure of arylamine N-acetyltransferase reveals a catalytic triad

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Cysteine Proteases and Their Inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

The emerging power of chemical genetics

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Chemical genetics: ligand-based discovery of gene function

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

Reassessment of Ellman's reagent

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900484-0

7 January 2021

10.1016/S0960-894X(03)00484-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12852958%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference